Astrocyte adenosine deaminase loss increases motor neuron toxicity in amyotrophic lateral sclerosis

Allen, S., Hall, B., Castelli, L. et al. (19 more authors) (2019) Astrocyte adenosine deaminase loss increases motor neuron toxicity in amyotrophic lateral sclerosis. Brain, 142 (3). pp. 586-605. ISSN 0006-8950

Abstract

Metadata

Authors/Creators:
  • Allen, S.
  • Hall, B.
  • Castelli, L.
  • Francis, L.
  • Woof, R.
  • Siskos, A.
  • Kouloura, E.
  • Gray, E.
  • Thompson, A.
  • Talbot, K.
  • Higginbottom, A.
  • Myszczynska, M.
  • Allen, C.
  • Stopford, M.
  • Hemingway, J.
  • Bauer, C.
  • Webster, C.
  • De Vos, K.
  • Turner, M.
  • Hautbergue, G.
  • Ferraiuolo, L.
  • Shaw, P. https://orcid.org/0000-0002-8925-2567
Copyright, Publisher and Additional Information: The Author(s) (2019). Published by Oxford University Press on behalf of the Guarantors of Brain. This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
Keywords: ALS; C9orf72; metabolism; inosine; adenosine deaminase
Dates:
  • Accepted: 22 November 2018
  • Published (online): 28 January 2019
  • Published: March 2019
Institution: The University of Sheffield
Academic Units: The University of Sheffield > Sheffield Teaching Hospitals
Funding Information:
FunderGrant number
MOTOR NEURONE DISEASE ASSOCIATIONAllen/Oct15/956-799
Depositing User: Symplectic Sheffield
Date Deposited: 11 Jan 2019 09:15
Last Modified: 22 Mar 2019 11:35
Status: Published
Publisher: Oxford University Press
Refereed: Yes
Identification Number: https://doi.org/10.1093/brain/awy353

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