Items where authors include "Tomlinson, I"

Article

Dennis, J, Tyrer, JP, Walker, LC et al. (121 more authors) (2022) Rare germline copy number variants (CNVs) and breast cancer risk. Communications Biology, 5. 65. ISSN 2399-3642

Park, HA, Neumeyer, S, Michailidou, K et al. (274 more authors) (2021) Mendelian randomisation study of smoking exposure in relation to breast cancer risk. British Journal of Cancer, 125. pp. 1135-1145. ISSN 0007-0920

Morra, A, Escala-Garcia, M, Beesley, J et al. (175 more authors) (2021) Association of germline genetic variants with breast cancer-specific survival in patient subgroups defined by clinic-pathological variables related to tumor biology and type of systemic treatment. Breast Cancer Research, 23 (1). 86.

Baxter, JS, Johnson, N, Tomczyk, K et al. (180 more authors) (2021) Functional annotation of the 2q35 breast cancer risk locus implicates a structural variant in influencing activity of a long-range enhancer element. The American Journal of Human Genetics, 108 (7). pp. 1190-1203. ISSN 0002-9297

Sirinukunwattana, K, Domingo, E, Richman, SD orcid.org/0000-0003-3993-5041 et al. (21 more authors) (2021) Image-based consensus molecular subtype classification (imCMS) of colorectal cancer using deep learning. Gut, 70. pp. 544-554. ISSN 0017-5749

Johnson, N, Maguire, S, Morra, A et al. (145 more authors) (2021) CYP3A7*1C allele: linking premenopausal oestrone and progesterone levels with risk of hormone receptor-positive breast cancers. British Journal of Cancer, 124 (4). pp. 842-854. ISSN 0007-0920

Dighe, SG, Chen, J, Yan, L et al. (70 more authors) (2020) Germline variation in the insulin-like growth factor pathway and risk of Barrett’s esophagus and esophageal adenocarcinoma. Carcinogenesis. ISSN 0143-3334

Malla, SB, Fisher, DJ, Domingo, E et al. (29 more authors) (2020) In-depth clinical and biological exploration of DNA Damage Immune Response (DDIR) as a biomarker for oxaliplatin use in colorectal cancer. Clinical Cancer Research. ISSN 1078-0432

Kramer, I, Hooning, MJ, Mavaddat, N et al. (264 more authors) (2020) Breast cancer polygenic risk score and contralateral breast cancer risk. The American Journal of Human Genetics, 107 (5). pp. 837-848. ISSN 0002-9297

Zhang, YD, Hurson, AN, Zhang, H et al. (102 more authors) (2020) Assessment of polygenic architecture and risk prediction based on common variants across fourteen cancers. Nature Communications, 11. 3353.

Zhang, H, Ahearn, TU, Lecarpentier, J et al. (269 more authors) (2020) Genome-wide association study identifies 32 novel breast cancer susceptibility loci from overall and subtype-specific analyses. Nature Genetics, 52 (6). pp. 572-581. ISSN 1061-4036

Escala-Garcia, M, Abraham, J, Andrulis, IL et al. (142 more authors) (2020) A network analysis to identify mediators of germline-driven differences in breast cancer prognosis. Nature Communications, 11 (1). 312.

Fachal, L, Aschard, H, Beesley, J et al. (338 more authors) (2020) Fine-mapping of 150 breast cancer risk regions identifies 191 likely target genes. Nature Genetics, 52 (1). pp. 56-73. ISSN 1061-4036

Ham-Karim, HA, Ebili, HO, Bradshaw, K et al. (5 more authors) (2019) Targeted next generation sequencing reveals a common genetic pathway for colorectal cancers with chromosomal instability and those with microsatellite and chromosome stability. Pathology - Research and Practice, 215 (7). 152445. ISSN 0344-0338

Mavaddat, N, Michailidou, K, Dennis, J et al. (266 more authors) (2019) Polygenic Risk Scores for Prediction of Breast Cancer and Breast Cancer Subtypes. The American Journal of Human Genetics, 104 (1). pp. 21-34. ISSN 0002-9297

Garcia-Dios, DA, Levi, D, Shah, V et al. (5 more authors) (2018) MED12, TERT promoter and RBM15 mutations in primary and recurrent phyllodes tumours. British Journal of Cancer, 118. pp. 277-284. ISSN 0007-0920

Lawler, M, Alsina, D, Adams, RA et al. (18 more authors) (2018) Critical research gaps and recommendations to inform research prioritisation for more effective prevention and improved outcomes in colorectal cancer. Gut, 67 (1). pp. 179-193. ISSN 0017-5749

Buas, MF, He, Q, Johnson, LG et al. (37 more authors) (2017) Germline variation in inflammation-related pathways and risk of Barrett's oesophagus and oesophageal adenocarcinoma. Gut, 66 (10). pp. 1739-1737. ISSN 0017-5749

Abbosh, C, Birkbak, NJ, Wilson, GA et al. (425 more authors) (2017) Phylogenetic ctDNA analysis depicts early stage lung cancer evolution. Nature, 545. pp. 446-451. ISSN 0028-0836

Liu, J, Lončar, I, Collée, JM et al. (97 more authors) (2016) rs2735383, located at a microRNA binding site in the 3'UTR of NBS1, is not associated with breast cancer risk. Scientific Reports, 6. p. 36874. ISSN 2045-2322

Gharahkhani, P, Fitzgerald, RC, Vaughan, TL et al. (66 more authors) (2016) Genome-wide association studies in oesophageal adenocarcinoma and Barrett's oesophagus: a large-scale meta-analysis. Lancet Oncology, 17 (10). pp. 1363-1373. ISSN 1470-2045

Chubb, D, Broderick, P, Dobbins, SE et al. (12 more authors) (2016) Rare disruptive mutations and their contribution to the heritable risk of colorectal cancer. Nature Communications, 7. 11883. ISSN 2041-1723

Day, FR, Ruth, KS, Thompson, DJ et al. (240 more authors) (2015) Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair. Nature Genetics, 47 (11). ISSN 1061-4036

Smith, CG, Fisher, D, Harris, R et al. (15 more authors) (2015) Analyses of 7,635 Patients with Colorectal Cancer Using Independent Training and Validation Cohorts Show That rs9929218 in CDH1 Is a Prognostic Marker of Survival. Clinical Cancer Research, 21 (15). pp. 3453-3461. ISSN 1078-0432

Darabi, H, McCue, K, Beesley, J et al. (126 more authors) (2015) Polymorphisms in a Putative Enhancer at the 10q21.2 Breast Cancer Risk Locus Regulate NRBF2 Expression. American Journal of Human Genetics .

Palles, C, Chegwidden, L, Li, X et al. (95 more authors) (2015) Polymorphisms Near TBX5 and GDF7 Are Associated With Increased Risk for Barrett's Esophagus. Gastroenterology, 148 (2). pp. 367-378. ISSN 0016-5085

Palles, C, Chegwidden, L, Li, X et al. (95 more authors) (2015) Polymorphisms Near TBX5 and GDF7 Are Associated With Increased Risk for Barrett’s Esophagus. Gastroenterology, 148 (2). pp. 367-378. ISSN 0016-5085

Ghoussaini, M, Edwards, SL, Michailidou, K et al. (209 more authors) (2014) Evidence that breast cancer risk at the 2q35 locus is mediated through IGFBP5 regulation. Nature Communications, 5. 4999. ISSN 2041-1723

Rosmarin, D, Palles, C, Church, D et al. (41 more authors) (2014) Genetic markers of toxicity from capecitabine and other fluorouracil-based regimens: investigation in the QUASAR2 study, systematic review, and meta-analysis. Journal of Clinical Oncology, 32 (10). 1031 - 1039. ISSN 0732-183X

Bojesen, SE, Pooley, KA, Johnatty, SE et al. (442 more authors) (2013) Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer. Nature Genetics, 45 (4). pp. 371-384. ISSN 1061-4036

Palles, C, Cazier, J-B, Howarth, KM et al. (36 more authors) (2013) Germline mutations affecting the proofreading domains of POLE and POLD1 predispose to colorectal adenomas and carcinomas. Nature Genetics, 45 (2). pp. 136-144. ISSN 1061-4036

Ghoussaini, M, Fletcher, O, Michailidou, K et al. (184 more authors) (2012) Genome-wide association analysis identifies three new breast cancer susceptibility loci. Nature Genetics, 44 (3). pp. 312-318. ISSN 1061-4036

Haiman, CA, Chen, GK, Vachon, CM et al. (128 more authors) (2011) A common variant at the TERT-CLPTM1L locus is associated with estrogen receptor-negative breast cancer. Nature Genetics, 43 (12). 1210. ISSN 1061-4036

Conference or Workshop Item

Seligmann, JF, Domingo, E, Fisher, D et al. (17 more authors) (2022) The clinical relevance of tumor RAS/TP53 dual mutation in early and metastatic colorectal cancer (CRC). In: 2022 ASCO Annual Meeting, 03-07 Jun 2022, Chicago, Il, USA and Online.