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Number of items: 38.


Álvarez-Rodríguez, B, Tiede, C, Hoste, ACR et al. (11 more authors) (2020) Characterization and applications of a Crimean-Congo hemorrhagic fever virus nucleoprotein-specific Affimer: Inhibitory effects in viral replication and development of colorimetric diagnostic tests. PLOS Neglected Tropical Diseases, 14 (6). e0008364. ISSN 1935-2727

King, RJ, Schuett, K, Tiede, C et al. (10 more authors) (2020) Fibrinogen interaction with complement C3: a potential therapeutic target to reduce thrombosis risk. Haematologica. ISSN 0390-6078

Adamson, H, Nicholl, A, Tiede, C et al. (9 more authors) (2019) Affimers as anti-idiotypic affinity reagents for pharmacokinetic analysis of biotherapeutics. BioTechniques, 67 (6). ISSN 0736-6205

Adamson, H, Ajayi, MO, Campbell, E et al. (10 more authors) (2019) Affimer–Enzyme–Inhibitor Switch Sensor for Rapid Wash-free Assays of Multimeric Proteins. ACS Sensors, 4 (11). pp. 3014-3022. ISSN 2379-3694

Arrata, I, Grison, CM, Coubrough, HM et al. (5 more authors) (2019) Control of conformation in α-helix mimicking aromatic oligoamide foldamers through interactions between adjacent side-chains. Organic and Biomolecular Chemistry, 17. pp. 3861-3867. ISSN 1477-0520

Kearney, KJ, Pechlivani, N, King, R et al. (13 more authors) (2019) Affimer proteins as a tool to modulate fibrinolysis, stabilize the blood clot and reduce bleeding complications. Blood, 133 (11). pp. 1233-1244. ISSN 0006-4971

Martin, HL, Bedford, R, Heseltine, SJ et al. (5 more authors) (2018) Non-immunoglobulin scaffold proteins: Precision tools for studying protein-protein interactions in cancer. New Biotechnology, 45. pp. 28-35. ISSN 1871-6784

Zhurauski, P, Arya, SK, Jolly, P et al. (4 more authors) (2018) Sensitive and selective Affimer-functionalised interdigitated electrode-based capacitive biosensor for Her4 protein tumour biomarker detection. Biosensors and Bioelectronics, 108. pp. 1-8. ISSN 0956-5663

Robinson, JI, Baxter, EW, Owen, RL et al. (13 more authors) (2018) Affimer proteins inhibit immune complex binding to FcγRIIIa with high specificity through competitive and allosteric modes of action. Proceedings of the National Academy of Sciences, 115 (1). E72-E81. ISSN 0027-8424

Xie, C, Tiede, C, Zhang, X et al. (6 more authors) (2017) Development of an Affimer-antibody combined immunological diagnosis kit for glypican-3. Scientific Reports, 7 (1). 9608. p. 9608. ISSN 2045-2322

Hughes, DJ, Tiede, C, Penswick, N et al. (12 more authors) (2017) Generation of specific inhibitors of SUMO-1– and SUMO-2/3–mediated protein-protein interactions using Affimer (Adhiron) technology. Science Signaling, 10 (505). eaaj2005. ISSN 1945-0877

Tang, AA-S, Tiede, C, Hughes, DJ et al. (2 more authors) (2017) Isolation of isoform-specific binding proteins (Affimers) by phage display using negative selection. Science Signaling, 10 (505). eaan0868. ISSN 1945-0877

Smith, GA, Fearnley, G, Abdul Zani, I et al. (4 more authors) (2017) Ubiquitination of basal VEGFR2 regulates signal transduction and endothelial function. Biology Open, 6 (10). pp. 1404-1415. ISSN 2046-6390

Tiede, C, Bedford, R, Heseltine, SJ et al. (43 more authors) (2017) Affimers proteins are versatile and renewable affinity reagents. eLife, 6. e24903. ISSN 2050-084X

Arrata, I, Barnard, A, Tomlinson, DC et al. (1 more author) (2017) Interfacing native and non-native peptides: using Affimers to recognise α-helix mimicking foldamers. Chemical Communications, 53 (19). pp. 2834-2837. ISSN 1359-7345

Webster, PJ, Littlejohns, AT, Gaunt, HJ et al. (17 more authors) (2017) Upregulated WEE1 protects endothelial cells of colorectal cancer liver metastases. Oncotarget, 8 (26). pp. 42288-42299. ISSN 1949-2553

Di Martino, E, Tomlinson, DC, Williams, SV et al. (1 more author) (2016) A place for precision medicine in bladder cancer: targeting the FGFRs. Future Oncology, 12 (19). pp. 2243-2263. ISSN 1479-6694

Pouessel, D, Neuzillet, Y, Mertens, LS et al. (35 more authors) (2016) Tumor Heterogeneity of Fibroblast Growth Factor Receptor 3 (FGFR3) Mutations in Invasive Bladder Cancer: Implications for Peri-Operative anti-FGFR3 Treatment. Annals of Oncology, 27 (7). pp. 1311-1316. ISSN 0923-7534

Sharma, R, Deacon, SE, Nowak, D et al. (7 more authors) (2016) Label-free electrochemical impedance biosensor to detect human interleukin-8 in serum with sub-pg/ml sensitivity. Biosensors and Bioelectronics, 80. pp. 607-613. ISSN 0956-5663

Fearnley, GW, Smith, GA, Abdul Zani, I et al. (9 more authors) (2016) VEGF-A isoforms program differential VEGFR2 signal transduction, trafficking and proteolysis. Biology Open, 2016 (5). pp. 571-583. ISSN 2046-6390

Smith, GA, Fearnley, GW, Zani, IA et al. (4 more authors) (2016) VEGFR2 trafficking, signaling and proteolysis is regulated by the ubiquitin isopeptidase USP8. Traffic, 17 (1). pp. 53-65. ISSN 1398-9219

Fisher, M, Williamson, DJ, Burslem, GM et al. (11 more authors) (2015) Trivalent Gd-DOTA reagents for modification of proteins. RSC Advances, 5 (116). 96194 - 96200. ISSN 2046-2069

Kyle, HF, Wickson, KF, Stott, J et al. (8 more authors) (2015) Exploration of the HIF-1α/p300 interface using peptide and Adhiron phage display technologies. Molecular Biosystems, 11 (10). 2738 - 2749. ISSN 1742-206X

Smith, GA, Fearnley, GW, Tomlinson, DC et al. (2 more authors) (2015) The cellular response to vascular endothelial growth factors requires co-ordinated signal transduction, trafficking and proteolysis. Bioscience Reports, 35 (5). e00253. ISSN 0144-8463

Wheway, G, Schmidts, M, Mans, DA et al. (75 more authors) (2015) An siRNA-based functional genomics screen for the identification of regulators of ciliogenesis and ciliopathy genes. Nature cell biology. ISSN 1465-7392

Smith, GA, Fearnley, GW, Harrison, MA et al. (3 more authors) (2015) Vascular endothelial growth factors: multitasking functionality in metabolism, health and disease. Journal of Inherited Metabolic Disease, 38 (4). 753 - 763. ISSN 0141-8955

Rawlings, AE, Bramble, JP, Tang, AAS et al. (6 more authors) (2015) Phage display selected magnetite interacting Adhirons for shape controlled nanoparticle synthesis. Chemical Science. ISSN 2041-6520

Nash, CE, Mavria, G, Baxter, EW et al. (7 more authors) (2015) Development and characterisation of a 3D multi-cellular in vitro model of normal human breast: a tool for cancer initiation studies. Oncotarget.

Barnard, A, Long, K, Martin, HL et al. (5 more authors) (2015) Selective and Potent Proteomimetic Inhibitors of Intracellular Protein-Protein Interactions. Angewandte Chemie, 127 (10). pp. 3003-3008. ISSN 0044-8249

Barnard, A, Long, K, Martin, HL et al. (5 more authors) (2015) Selective and potent proteomimetic inhibitors of intracellular protein-protein interactions. Angewandte Chemie - International Edition, 54 (10). pp. 2960-2965. ISSN 1433-7851

Tiede, C, Tang, AA, Deacon, SE et al. (8 more authors) (2014) Adhiron: a stable and versatile peptide display scaffold for molecular recognition applications. Protein Engineering Design and Selection, 27 (5). 145 - 155 (10). ISSN 1741-0126

Stadler, LK, Tomlinson, DC, Lee, T et al. (2 more authors) (2014) The use of a neutral peptide aptamer scaffold to anchor BH3 peptides constitutes a viable approach to studying their function. Cell Death and Disease, 5. e1037. e1037 - e1037. ISSN 2041-4889

Martin, HL, Smith, L and Tomlinson, DC (2014) Multidrug-resistant breast cancer: Current perspectives. Breast Cancer: Targets and Therapy, 6. 1 - 13. ISSN 1179-1314

Adams, M, Cookson, VJ, Higgins, J et al. (5 more authors) (2014) A high-throughput assay to identify modifiers of premature chromosome condensation. Journal of Biomolecular Screening, 19 (1). pp. 176-183. ISSN 1087-0571

Martin, HL, Adams, M, Higgins, J et al. (6 more authors) (2014) High-content, high-throughput screening for the identification of cytotoxic compounds based on cell morphology and cell proliferation markers. PLoS One, 9 (2). e88338. ISSN 1932-6203

Fearnley, GW, Smith, GA, Odell, AF et al. (5 more authors) (2014) Vascular endothelial growth factor A-stimulated signaling from endosomes in primary endothelial cells. Methods in Enzymology, 535. 265 - 292. ISSN 0076-6879

Proceedings Paper

Bedford, R, Tiede, C, Hughes, R et al. (4 more authors) (2017) Alternative reagents to antibodies in imaging applications. In: Biophysical Reviews. 19th IUPAB Congress, 16-20 Jul 2017, Edinburgh, UK. Springer , pp. 299-308.

Boissinot, M, King, H, Adams, M et al. (7 more authors) (2016) Ectopic expression of microRNA-1300 in adult and paediatric glioma cells induces cytokinesis failure and apoptosis via ECT2. In: Neuro-Oncology. 12th Meeting of the European Association of Neuro-Oncology, 12-16 Oct 2016, Mannheim/Heidelberg, Germany. Oxford University Press , iv18-iv18.

This list was generated on Sun Jul 5 12:30:29 2020 BST.