Items where authors include "Mottram, Jeremy Charles"

Article

Russell, Catherine, Carter, Jennifer, Borgia, Juliet Marie et al. (7 more authors) (2023) Bromodomain Factor 5 as a Target for Antileishmanial Drug Discovery. ACS Infectious Diseases. ISSN 2373-8227

Black, Jennifer Ann, Klinger, Christen, Lemgruber, Leandro et al. (3 more authors) (2023) AAK1-like: a putative pseudokinase with potential roles in cargo uptake in bloodstream form Trypanosoma brucei parasites. Journal of Eukaryotic Microbiology. ISSN 1066-5234

Mottram, Jeremy Charles orcid.org/0000-0001-5574-3766 (2023) Autophagy in protists and their hosts : When, how and why? Autophagy. p. 2149211. ISSN 1554-8635

Mottram, Jeremy Charles orcid.org/0000-0001-5574-3766 (2023) Genome sequence of Leishmania mexicana MNYC/BZ/62/M379 expressing Cas9 and T7 RNA polymerase. Wellcome Open Research. 294. ISSN 2398-502X

Costa, Tatiana F. R., Goundry, Amy, Morrot, Alexandre et al. (3 more authors) (2022) Trypanosoma brucei rhodesiense INHIBITOR OF CYSTEINE PEPTIDASE (ICP) IS REQUIRED FOR VIRULENCE IN MICE AND TO ATTENUATE THE INFLAMMATORY RESPONSE. International Journal of Molecular Sciences. ISSN 1422-0067 (In Press)

Carnielli, Juliana B.T., Dave, Anuja, Romano, Audrey et al. (7 more authors) (2022) 3’Nucleotidase/nuclease is required for Leishmania infantum clinical isolate susceptibility to miltefosine. EBioMedicine. 104378. ISSN 2352-3964

Geoghegan, Vincent, Carnielli, Juliana B.T., Jones, Nathaniel orcid.org/0000-0001-7328-4487 et al. (6 more authors) (2022) CLK1/CLK2 driven signalling at the Leishmania kinetochore is captured by spatially referenced proximity phosphoproteomics. Communications Biology. ISSN 2399-3642

Rath, Carolina T, Vivarini, Aislan C., Vitorino dos Santos,, José et al. (7 more authors) (2022) Toll-Like Receptor 3 (TLR3) Is Engaged in the Intracellular Survival of the Protozoan Parasite Leishmania (Leishmania) amazonensis. Infection and Immunity. ISSN 1098-5522

Geoghegan, Vincent, Mottram, Jeremy Charles orcid.org/0000-0001-5574-3766 and Jones, Nathaniel orcid.org/0000-0001-7328-4487 (2022) Tag thy neighbour: nanometre-scale insights into kinetoplastid parasites with proximity dependent biotinylation. Frontiers in cellular and infection microbiology. ISSN 2235-2988

Forrester, Sarah Jayne, Goundry, Amy Louise, Torres Dias, Bruna et al. (5 more authors) (2022) Tissue specific dual RNA-seq defines host-parasite interplay in murine visceral leishmaniasis caused by Leishmania donovani and Leishmania infantum. Microbiology spectrum. 00679. ISSN 2165-0497

Torres Dias, Bruna, Goundry, Amy, Vivarini, Aislan C. et al. (4 more authors) (2022) TLR2, TLR4 and Protein kinase R (PKR) induced Type I Interferon sustains infection of Leishmania donovani in macrophages. Frontiers in immunology. ISSN 1664-3224 (In Press)

Grace, Cooper Alastair, Forrester, Sarah Jayne, Costa Silva, Vladimir et al. (8 more authors) (2021) Candidates for Balancing Selection in Leishmania donovani Complex Parasites. Molecular Biology and Evolution. evab265. ISSN 0737-4038

Saldivia, Manuel, Wollman, Adam J.M., Carnielli, Juliana B.T. et al. (5 more authors) (2021) A CLK1-KKT2 signaling pathway regulating kinetochore assembly in Trypanosoma brucei. MBio. e00687-21. ISSN 2150-7511

Corrales, Rosa Milagros, Vaselek, Slavica, Neish, Rachel et al. (10 more authors) (2021) The kinesin of the flagellum attachment zone in Leishmania is required for cell morphogenesis, cell division and virulence in the mammalian host. PLOS PATHOGENS. e1009666. ISSN 1553-7366

Petersen, Antonio Luis de O. A., Cull, Benjamin, Simões Dias, Beatriz R. et al. (5 more authors) (2021) 17-AAG-induced activation of the autophagic pathway in Leishmania is associated with parasite death. Microorganisms. 1089. ISSN 2076-2607

Belbelazi, Asma, Neish, Rachel, Carr, Martin et al. (2 more authors) (2021) Divergent cytochrome c maturation system in kinetoplastid protists. MBio. e00166-21. ISSN 2150-7511

Gonçalves, Camila Silva, Catta-Preta, Carolina Moura Costa, Repolês, Bruno et al. (4 more authors) (2021) Importance of Angomonas deanei KAP4 for kDNA arrangement, cell division and maintenance of the host-bacterium relationship. Scientific Reports. 9210. ISSN 2045-2322

Davey, John William, Catta-Preta, Carolina M. C., James, Sally et al. (4 more authors) (2020) Chromosomal assembly of the nuclear genome of the endosymbiontbearing trypanosomatid Angomonas deanei. G3: Genes, Genomes, Genetics. jkaa018. ISSN 2160-1836

Halliday, Clare, Yanase, Ryuji, Catta-Preta, Carolina Moura Costa et al. (6 more authors) (2020) Role for the flagellum attachment zone in Leishmania anterior cell tip morphogenesis. PLOS PATHOGENS. ISSN 1553-7366

Saldivia Concepcion, Manuel Alejandro, Fang, Eric, Ma, Xiaolei et al. (20 more authors) (2020) Targeting the trypanosome kinetochore with CLK1 protein kinase inhibitors. Nature Microbiology. pp. 1207-1216. ISSN 2058-5276

Damianou, Andreas, Burge, Rebecca, Catta-Preta, Carolina M. C. et al. (7 more authors) (2020) Essential roles for deubiquitination in Leishmania life cycle progression. PLOS PATHOGENS. ISSN 1553-7366 (In Press)

Black, Jennifer Ann, Crouch, Kathryn, Lemgruber, Leandro et al. (5 more authors) (2020) Trypanosoma brucei ATR Links DNA Damage Signaling during Antigenic Variation with Regulation of RNA Polymerase I-Transcribed Surface Antigen. Cell reports. e5. pp. 836-851. ISSN 2211-1247

Grewal, Jaspreet, Catta Preta, Carolina, Brown, Elaine et al. (2 more authors) (2019) Evaluation of Clan CD C11 peptidase PNT1 and other Leishmania mexicana cysteine peptidases as potential drug targets. BIOCHIMIE. ISSN 0300-9084

Brambilla Carnielli Trindade, Juliana, Monti-Rocha, Renata, Costa, Dorcas Lamounier. et al. (7 more authors) (2019) Natural Resistance of Leishmania infantum to Miltefosine Contributes to the Low Efficacy in the Treatment of Visceral Leishmaniasis in Brazil. American journal of tropical medicine and hygiene. pp. 789-794. ISSN 1476-1645

Torres Dias, Bruna, Teixeira, Karina L., Godinho, Joseane P. et al. (6 more authors) (2019) Neutrophil elastase promotes Leishmania donovani infection via interferon-β. The FASEB Journal. pp. 10794-10807. ISSN 1530-6860

Sunter, Jack D., Yanase, Ryuji, Wang, Ziyin et al. (7 more authors) (2019) Leishmania flagellum attachment zone is critical for flagellar pocket shape, development in the sand fly and pathogenicity in the host. Proceedings of the National Academy of Sciences of the United States of America. pp. 6351-6360. ISSN 1091-6490

Ronet, Catherine, Passelli, Katiuska, Charmoy, Melanie et al. (10 more authors) (2018) TLR2 signaling in skin non-hematopoietic cells induces early neutrophil recruitment in response to Leishmania major infection. Journal of investigative dermatology. ISSN 1523-1747

Damasceno, Jeziel D, Obonaga, Ricardo, Silva, Gabriel L A et al. (6 more authors) (2018) Conditional genome engineering reveals canonical and divergent roles for the Hus1 component of the 9-1-1 complex in the maintenance of the plastic genome of Leishmania. Nucleic Acids Research. pp. 11835-11846. ISSN 0305-1048

Rao, Srinivasa P S, Barrett, Michael, Dranoff, Glenn et al. (16 more authors) (2018) Drug Discovery for Kinetoplastid Diseases : Future Directions. ACS Infectious Diseases. ISSN 2373-8227

Bussotti, Giovanni, Gouzelou, Evi, Cortes Boite, Mariana et al. (27 more authors) (2018) Leishmania genome dynamics during environmental adaptation reveals strain-specific differences in gene copy number variation, karyotype instability, and telomeric amplification. MBio. e01399-18. ISSN 2150-7511

Mottram, Jeremy Charles orcid.org/0000-0001-5574-3766, Jeffares, Daniel orcid.org/0000-0001-7320-0706, Brambilla Carnielli Trindade, Juliana et al. (10 more authors) (2018) A Leishmania infantum genetic marker associated with miltefosine treatment failure for visceral leishmaniasis. EBioMedicine. ISSN 2352-3964

Frey, Philipp, Chartomastsidou, Roula, Kiefer, Werner et al. (3 more authors) (2018) New aziridine-based inhibitors of cathepsin L-like cysteine proteases with selectivity for the Leishmania cysteine protease LmCPB2.8. European Journal of Medicinal Chemistry. pp. 587-597.

Jones, Nathaniel orcid.org/0000-0001-7328-4487, Catta Preta, Carolina, Lima, Ana Paula C.A. et al. (1 more author) (2018) Genetically Validated Drug Targets in Leishmania: Current Knowledge and Future Prospects. ACS Infectious Diseases. pp. 467-477. ISSN 2373-8227

Mottram, Jeremy Charles orcid.org/0000-0001-5574-3766, Pierre-Andre, Casgrain, McMaster, W. Robert et al. (3 more authors) (2016) Cysteine peptidase B regulates Leishmania mexicana virulence through the modulation of GP63 expression. PLOS PATHOGENS. e1005658. ISSN 1553-7366

Grewal, Jaspreet, McLuskey, Karen, Das, Debanu et al. (9 more authors) (2016) PNT1 is a C11 Cysteine Peptidase Essential for Replication of the Trypanosome Kinetoplast. Journal of Biological Chemistry. pp. 9492-9500. ISSN 1083-351X

Duncan, Samuel M., Myburgh, Elmarie orcid.org/0000-0002-2007-5902, Philipon, Cintia et al. (4 more authors) (2016) Conditional gene deletion with DiCre demonstrates an essential role for CRK3 in Leishmania mexicana cell cycle regulation. Molecular Microbiology. pp. 931-944. ISSN 0950-382X

McLuskey, Karen, Grewal, Jaspreet, Das, Debanu et al. (7 more authors) (2016) Crystal Structure and Activity Studies of the C11 Cysteine Peptidase from Parabacteroides merdae in the Human Gut Microbiome. Journal of Biological Chemistry. pp. 9482-9491. ISSN 1083-351X