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Algasaier, S.I., Finger, L.D., Bennet, I.A. et al. (1 more author) (2018) Flap endonuclease 1 mutations A159V and E160D cause genomic instability by slowing reaction on double-flap substrates. Biochemistry, 57 (50). pp. 6838-6847. ISSN 0006-2960

Thompson, M.J., Gotham, V., Ciani, B. et al. (1 more author) (2018) A conserved loop-wedge motif moderates reaction site search and recognition by FEN1. Nucleic Acids Research. ISSN 0305-1048

Bennet, I., Finger, L.D., Baxter, N.J. et al. (8 more authors) (2018) Regional Conformational Flexibility Couples Substrate Specificity and Scissile Phosphate Diester Selectivity in Human Flap Endonuclease 1. Nucleic Acids Research. gky293. ISSN 0305-1048

Shaw, S.J., Finger, L.D. and Grasby, J.A. (2017) Human Exonuclease 1 Threads 5'-Flap Substrates Through its Helical Arch. Biochemistry. ISSN 0006-2960

Tsutakawa, S.E., Thompson, M.J., Arvai, A.S. et al. (14 more authors) (2017) Phosphate steering by Flap Endonuclease 1 promotes 5ยด-flap specificity and incision to prevent genome instability. Nature Communications, 8. 15855 . ISSN 2041-1723

Algasaier, S.I., Exell, J.C., Bennet, I.A. et al. (6 more authors) (2016) DNA and Protein Requirements for Substrate Conformational Changes Necessary for Human Flap Endonuclease-1 Catalyzed Reaction. The Journal of Biological Chemistry, 291 (15). pp. 8258-8268. ISSN 0021-9258

Exell , J.C., Thompson , M.J., Finger, L.D. et al. (11 more authors) (2016) Cellular Active N-Hydroxyurea FEN1 Inhibitors Block Substrate Entry to the Active Site. Nature Chemical Biology, 12. pp. 815-821. ISSN 1552-4450

Kime, L., Clarke, J.E., Romero, D.A. et al. (2 more authors) (2014) Adjacent single-stranded regions mediate processing of tRNA precursors by RNase E direct entry. Nucleic Acids Research, 42 (7). pp. 4577-4589. ISSN 0305-1048

Patel, N., Atack, J.M., Finger, L.D. et al. (6 more authors) (2012) Flap endonucleases pass 5 '-flaps through a flexible arch using a disorder-thread-order mechanism to confer specificity for free 5 '-ends. Nucleic Acids Research, 40 (10). pp. 4507-4519. ISSN 0305-1048

This list was generated on Sun Oct 20 06:12:36 2019 BST.