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Number of items at this level: 65.

A

Adams, WC, Chen, Y-H, Kratchmarov, R et al. (10 more authors) (2016) Anabolism-Associated Mitochondrial Stasis Driving Lymphocyte Differentiation over Self-Renewal. Cell Reports, 17 (12). pp. 3142-3152. ISSN 2211-1247

Agathanggelou, A, Smith, E, Davies, NJ et al. (20 more authors) (2017) USP7 inhibition alters homologous recombination repair and targets CLL cells independently of ATM/p53 functional status. Blood, 130 (2). pp. 156-166. ISSN 0006-4971

Arumugakani, G, Stephenson, SJ, Newton, DJ orcid.org/0000-0002-0214-1486 et al. (5 more authors) (2017) Early emergence of CD19-negative human antibody secreting cells at the plasmablast to plasma cell transition. Journal of Immunology, 198 (12). pp. 4618-4628. ISSN 0022-1767

B

Barbarulo, A, Iansante, V, Chaidos, A et al. (7 more authors) (2013) Poly(ADP-ribose) polymerase family member 14 (PARP14) is a novel effector of the JNK2-dependent pro-survival signal in multiple myeloma. Oncogene, 32 (36). pp. 4231-4242. ISSN 0950-9232

Barr, PM, Brown, JR, Hillmen, P orcid.org/0000-0001-5617-4403 et al. (19 more authors) (2017) Impact of ibrutinib dose adherence on therapeutic efficacy in patients with previously treated CLL/SLL. Blood, 129 (19). pp. 2612-2615. ISSN 0006-4971

Bigley, V, Maisuria, S, Cytlak, U et al. (20 more authors) (2018) Biallelic interferon regulatory factor 8 mutation: A complex immunodeficiency syndrome with dendritic cell deficiency, monocytopenia, and immune dysregulation. Journal of Allergy and Clinical Immunology, 141 (6). pp. 2234-2248. ISSN 0091-6749

Braga, FAV, Hertoghs, KML, Kragten, NAM et al. (16 more authors) (2015) The Blimp-1 homologue Hobit identifies effector-type lymphocytes in humans. European Journal of Immunology, 45 (10). 2945 - 2958. ISSN 0014-2980

Briones, MA, Coombes, JD, Mellone, M et al. (12 more authors) (2016) The role of osteopontin isoforms in cholangiocarcinoma. In: Hepatology. The 67th Annual Meeting of the American Association for the Study of Liver Diseases: The Liver Meeting 2016, 11-15 Nov 2016, Massachusetts, United States. Wiley , 235A-235A.

Briones-Orta, MA, Coombes, JD, Mellone, M et al. (11 more authors) (2015) Osteopontin‐c isoform promotes a mesenchymal phenotype in human cholangiocarcinoma cells. In: Hepatology. 66th Annual Meeting of the American Association for the Study of Liver Diseases: The Liver Meeting 2015, 13-17 Nov 2015, San Francisco, CA, USA. Wiley , 1171A-1171A.

Brown, JR, Hillmen, P orcid.org/0000-0001-5617-4403, O'Brien, S et al. (27 more authors) (2018) Extended follow-up and impact of high-risk prognostic factors from the phase 3 RESONATE(TM) study in patients with previously treated CLL/SLL. Leukemia, 32. pp. 83-91. ISSN 0887-6924

Brown, JR, Moslehi, J, O' Brien, S et al. (24 more authors) (2017) Characterization Of Atrial Fibrillation Adverse Events Reported In Ibrutinib Randomized Controlled Registration Trials. Haematologica, 102 (10). pp. 1796-1805. ISSN 0390-6078

Bubici, C and Papa, S orcid.org/0000-0002-8369-6538 (2014) JNK signalling in cancer: in need of new, smarter therapeutic targets. British Journal of Pharmacology, 171 (1). pp. 24-37. ISSN 0007-1188

Bubici, C and Papa, S orcid.org/0000-0002-8369-6538 (2015) Starving cancer cells of sugar could be the key to future treatment. The Conversation.

Buehler, A, Wendtner, C-M, Kipps, TJ et al. (17 more authors) (2016) Lenalidomide treatment and prognostic markers in relapsed or refractory chronic lymphocytic leukemia: data from the prospective, multicenter phase-II CLL-009 trial. Blood Cancer Journal, 6. ARTN e404. ISSN 2044-5385

Burger, J, Tedeschi, A, Barr, PM et al. (32 more authors) (2016) International, randomized phase 3 study results: Ibrutinib versus Chlorambucil in patients 65 years and older with treatment-naive CLL (RESONATE-2 (TM)). In: Oncology Research and Treatment. Annual conference of the German, Austrian and Swiss Societies for Haematology and Medical Oncology, 14-18 Oct 2016, Leipzig, Germany. Karger Publishers , p. 6.

Burger, JA, Tedeschi, A, Barr, PM et al. (31 more authors) (2015) Ibrutinib as Initial Therapy for Patients with Chronic Lymphocytic Leukemia. New England Journal of Medicine, 373 (25). pp. 2425-2437. ISSN 0028-4793

C

Care, MA, Stephenson, SJ, Barnes, NA et al. (7 more authors) (2016) Network analysis identifies proinflammatory plasma cell polarization for secretion of ISG15 in human autoimmunity. Journal of Immunology, 197 (4). pp. 1447-1459. ISSN 0022-1767

Care, MA, Westhead, DR and Tooze, RM (2015) Gene expression meta-analysis reveals immune response convergence on the IFNγ gamma-STAT1-IRF1 axis and adaptive immune resistance mechanisms in lymphoma. Genome Medicine, 7. 96. ISSN 1756-994X

Chinen, T, Kannan, AK, Levine, AG et al. (7 more authors) (2016) An essential role for the IL-2 receptor in Treg cell function. Nature Immunology, 17 (11). pp. 1322-1333. ISSN 1529-2908

Choy, PM, Sufi, J, Glaser, S et al. (7 more authors) (2015) Inhibition of mapk signalling promotes cell cycle arrest and sensitises intrahepatic cholangiocarcinoma cells to chemotherapy. In: Gut. 2nd Digestive Disorders Federation Conference, 22-25 Jun 2015, London, UK. BMJ Publishing Group , A458-A458.

D

De Silva, NS, Anderson, MM, Carette, A et al. (4 more authors) (2016) Transcription factors of the alternative NF-κB pathway are required for germinal center B-cell development. Proceedings of the National Academy of Sciences, 113 (32). pp. 9063-9068. ISSN 0027-8424

Dennis, M, Culligan, D, Karamitros, D et al. (8 more authors) (2013) Lenalidomide monotherapy and in combination with cytarabine, daunorubicin and etoposide for high-risk myelodysplasia and acute myeloid leukaemia with chromosome 5 abnormalities. Leukemia Research Reports, 2 (2). pp. 70-74. ISSN 2213-0489

G

Gillespie, J, Ross, RL, Corinaldesi, C et al. (7 more authors) (2018) Transforming Growth Factor β Activation Primes Canonical Wnt Signaling Through Down-Regulation of Axin-2. Arthritis & Rheumatology, 70 (6). pp. 932-942. ISSN 2326-5191

Grinberg-Bleyer, Y, Caron, R, Seeley, JJ et al. (5 more authors) (2018) The Alternative NF-κB Pathway in Regulatory T Cell Homeostasis and Suppressive Function. The Journal of Immunology, 200 (7). pp. 2362-2371. ISSN 0022-1767

Grinberg-Bleyer, Y, Oh, H, Desrichard, A et al. (7 more authors) (2017) NF-κB c-Rel Is Crucial for the Regulatory T Cell Immune Checkpoint in Cancer. Cell, 170 (6). 1096-1108.e13. ISSN 0092-8674

H

Heise, N and Klein, U orcid.org/0000-0002-4789-967X (2017) Somatic hypermutation and affinity maturation analysis using the 4-hydroxy-3-nitrophenyl-acetyl (NP) system. In: Calado, DP, (ed.) Germinal Centers. Methods in Molecular Biology, 1623 . Springer (Humana) , pp. 191-208. ISBN 978-1-4939-7094-0

Howard, DR orcid.org/0000-0003-3333-9783, Munir, T, Hockaday, AM et al. (7 more authors) (2016) Chemotherapy plus Ofatumumab at Standard or Mega dose in relapsed CLL (COSMIC) trial: study protocol for a phase II randomised controlled trial. Trials, 17. 456. ISSN 1745-6215

Howard, DR orcid.org/0000-0003-3333-9783, Munir, T, McParland, L et al. (9 more authors) (2017) Clinical effectiveness and cost-effectiveness results from the randomised, phase IIB trial in previously untreated patients with chronic lymphocytic leukaemia to compare fludarabine, cyclophosphamide and rituximab with fludarabine, cyclophosphamide, mitoxantrone and low dose rituximab: the Attenuated dose Rituximab with ChemoTherapy In Chronic lymphocytic leukaemia (ARCTIC) trial. Health Technology Assessment, 21 (28). ISSN 1366-5278

Howard, DR orcid.org/0000-0003-3333-9783, Munir, T, McParland, L et al. (12 more authors) (2017) Results of the randomized phase IIB ARCTIC trial of low dose Rituximab in previously untreated CLL. Leukemia, 31. pp. 2416-2425. ISSN 0887-6924

Hurst, CD orcid.org/0000-0001-7719-1325, Alder, O, Platt, FM et al. (15 more authors) (2017) Genomic Subtypes of Non-Invasive Bladder Cancer with Distinct Metabolic Profile and Female Gender Bias in KDM6A Mutation Frequency. Cancer Cell, 32 (5). pp. 701-715. ISSN 1535-6108

I

Iansante, V, Choy, PM, Chokshi, S et al. (4 more authors) (2015) Addressing the interplay between apoptosis and glucose metabolism in liver cirrhosis and HCC. In: Gut. 2nd Digestive Disorders Federation Conference, 22-25 Jun 2015, London, UK. BMJ Publishing Group , A12-A12.

Iansante, V, Choy, PM, Chokshi, S et al. (4 more authors) (2015) Increased aerobic glycolysis is associated with poor outcome and suppression of apoptosis in human liver cirrhosis and HCC. In: Journal of Hepatology. The International Liver Congress 2015: 50th Annual meeting of the European Association for the Study of the Liver, 22-26 Apr 2015, Vienna, Austria. Elsevier , S427-S427.

Iansante, V, Choy, PM, Fung, SW et al. (8 more authors) (2014) Upregulation of a novel protein in HCC enhances cancer cell survival by suppressing specific apoptotic effectors. In: Journal of Hepatology. The International Liver Congress 2014 – 49th Annual meeting of the European Association for the Study of the Liver, 09-13 Apr 2014, London, UK. Elsevier , S89-S89.

Iansante, V, Choy, PM, Fung, SW et al. (10 more authors) (2015) PARP14 promotes the Warburg effect in hepatocellular carcinoma by inhibiting JNK1-dependent PKM2 phosphorylation and activation. Nature Communications, 6. ISSN 2041-1723

K

Kennedy, R and Klein, U orcid.org/0000-0002-4789-967X (2018) Aberrant Activation of NF-κB Signalling in Aggressive Lymphoid Malignancies. Cells, 7 (11). ARTN 189. ISSN 2073-4409

Kirby, AC, Newton, DJ orcid.org/0000-0002-0214-1486, Carding, SR et al. (1 more author) (2007) Evidence for the involvement of lung-specific γδ T cell subsets in local responses to Streptococcus pneumoniae infection. European Journal of Immunology, 37 (12). pp. 3404-3413. ISSN 0014-2980

Kreuz, S, Holmes, KB, Tooze, RM et al. (1 more author) (2015) Loss of PIM2 enhances the anti-proliferative effect of the pan-PIM kinase inhibitor AZD1208 in non-Hodgkin lymphomas. Molecular Cancer, 14. 205. ISSN 1476-4598

Kwok, M, Davies, N, Agathanggelou, A et al. (12 more authors) (2016) ATR inhibition induces synthetic lethality and overcomes chemoresistance in TP53- or ATM-defective chronic lymphocytic leukemia cells. Blood, 127 (5). pp. 582-595. ISSN 0006-4971

Kwok, M, Rawstron, AC, Varghese, A et al. (6 more authors) (2016) Minimal residual disease is an independent predictor for 10-year survival in CLL. Blood, 128 (24). pp. 2770-2773. ISSN 0006-4971

L

Lee, NCW, Carella, MA, Papa, S orcid.org/0000-0002-8369-6538 et al. (1 more author) (2018) High Expression of Glycolytic Genes in Cirrhosis Correlates With the Risk of Developing Liver Cancer. Frontiers in Cell and Developmental Biology, 6. 138. ISSN 2296-634X

Li, X, Gadzinsky, A, Gong, L et al. (9 more authors) (2018) Cbl Ubiquitin Ligases Control B Cell Exit from the Germinal-Center Reaction. Immunity, 48 (3). 530-541.e6. ISSN 1074-7613

M

Mace, EM, Bigley, V, Gunesch, JT et al. (30 more authors) (2017) Biallelic mutations in IRF8 impair human NK cell maturation and function. Journal of Clinical Investigation, 127 (1). pp. 306-320. ISSN 0021-9738

Manka, P, Coombes, JD, Boosman, R et al. (3 more authors) (2018) Thyroid hormone in the regulation of hepatocellular carcinoma and its microenvironment. Cancer Letters, 419. pp. 175-186. ISSN 0304-3835

Milanovic, M, Heise, N, De Silva, NS et al. (6 more authors) (2017) Differential requirements for the canonical NF-κB transcription factors c-REL and RELA during the generation and activation of mature B cells. Immunology and Cell Biology, 95 (3). pp. 261-271. ISSN 0818-9641

Munir, T, Howard, DR orcid.org/0000-0003-3333-9783, McParland, L et al. (12 more authors) (2017) Results of the randomized phase IIB ADMIRE trial of FCR with or without mitoxantrone in previously untreated CLL. Leukemia, 31 (10). pp. 2085-2093. ISSN 0887-6924

O

Oh, H, Grinberg-Bleyer, Y, Liao, W et al. (11 more authors) (2017) An NF-κB Transcription-Factor-Dependent Lineage-Specific Transcriptional Program Promotes Regulatory T Cell Identity and Function. Immunity, 47 (3). 450-465.e5. ISSN 1074-7613

P

Papa, S orcid.org/0000-0002-8369-6538 and Bubici, C (2018) Feeding the Hedgehog: A new meaning for JNK signalling in liver regeneration. Journal of Hepatology, 69 (3). pp. 572-574. ISSN 0168-8278

Papa, S orcid.org/0000-0002-8369-6538 and Bubici, C (2016) Linking apoptosis to cancer metabolism: Another missing piece of JuNK. Molecular & Cellular Oncology, 3 (2). e1103398. ISSN 2372-3556

Papa, S orcid.org/0000-0002-8369-6538, Lee, N and Bubici, C (2018) Deciphering preventive and prognostic biomarkers of liver cancer. In: NCRI Cancer Conference abstracts. NCRI Cancer Conference 2018, 04-06 Nov 2018. NCRI .

Parrish, C, Scott, GB, Migneco, G et al. (13 more authors) (2015) Oncolytic reovirus enhances rituximab-mediated antibody-dependent cellular cytotoxicity against chronic lymphocytic leukaemia. Leukemia, 29 (9). 1799 - 1810. ISSN 0887-6924

Peacock-Young, B, Macrae, FL orcid.org/0000-0002-7092-0422, Newton, DJ orcid.org/0000-0002-0214-1486 et al. (2 more authors) (2018) The prothrombotic state in paroxysmal nocturnal hemoglobinuria: a multifaceted source. Haematologica, 103 (1). pp. 9-17. ISSN 0390-6078

R

Rawstron, A, Cohen, D, de Tute, R et al. (8 more authors) (2015) BONE MARROW IS MORE SENSITIVE THAN PERIPHERAL BLOOD FOR DETECTION OF MRD IN CLL AND PROVIDES A MORE RELIABLE PREDICTION OF OUTCOME ACROSS DIFFERENT TREATMENTS. In: European Haematology Association Congress, 11-14 Jun 2015, Vienna, Austria.

Rawstron, AC, Ssemaganda, A, de Tute, R et al. (11 more authors) (2017) Monoclonal B-cell lymphocytosis in a hospital-based UK population and a rural Ugandan population: a cross-sectional study. Lancet Haematology, 4 (7). e334-e340. ISSN 2352-3026

Riemann, M, Andreas, N, Fedoseeva, M et al. (7 more authors) (2017) Central immune tolerance depends on crosstalk between the classical and alternative NF-κB pathways in medullary thymic epithelial cells. Journal of Autoimmunity, 81. pp. 56-67. ISSN 0896-8411

Ryan, CE, Sahaf, B, Logan, AC et al. (13 more authors) (2016) Ibrutinib efficacy and tolerability in patients with relapsed chronic lymphocytic leukemia following allogeneic HCT. Blood, 128 (25). pp. 2899-2908. ISSN 0006-4971

S

Salakhieva, DV, Sadreev, II orcid.org/0000-0003-2628-8287, Chen, MZQ et al. (4 more authors) (2016) Kinetic regulation of multi-ligand binding proteins. BMC Systems Biology, 10. 32.

Savic, S, Ouboussad, L, Dickie, LJ et al. (10 more authors) (2014) TLR dependent XBP-1 activation induces an autocrine loop in rheumatoid arthritis synoviocytes. Journal of Autoimmunity, 50. 59 - 66. ISSN 0896-8411

Sha, C, Barrans, S, Care, MA et al. (4 more authors) (2015) Transferring genomics to the clinic: distinguishing Burkitt and diffuse large B cell lymphomas. Genome Medicine: medicine in the post-genomic era, 7. 64. ISSN 1756-994X

Sinfield, JK, Das, A, Ball, SG et al. (3 more authors) (2013) P38 MAPK alpha mediates cytokine-induced IL-6 and MMP-3 expression in human cardiac fibroblasts. Biochemical and Biophysical Research Communications, 430 (1). 419 - 424. ISSN 0006-291X

V

Varghese, A, Howard, DR orcid.org/0000-0003-3333-9783, Pocock, C et al. (9 more authors) (2017) Eradication of minimal residual disease improves overall and progression free survival in patients with chronic lymphocytic leukaemia, evidence from NCRN CLL207: A Phase II trial assessing alemtuzumab consolidation. British Journal of Haematology, 176 (4). pp. 573-582. ISSN 0007-1048

Varghese, AM, Rawstron, A orcid.org/0000-0003-0798-9790, Newton, D orcid.org/0000-0002-0214-1486 et al. (5 more authors) (2018) Highly selective SYK inhibitor, GSK143, abrogates survival signals in chronic lymphocytic leukaemia. British Journal of Haematology, 182 (6). pp. 927-930. ISSN 0007-1048

Verzella, D, Bennett, J, Fischietti, M et al. (17 more authors) (2018) GADD45β Loss Ablates Innate Immunosuppression in Cancer. Cancer Research, 78 (5). pp. 1275-1292. ISSN 0008-5472

Vrzalikova, K, Ibrahim, M, Vockerodt, M et al. (19 more authors) (2017) S1PR1 drives a feedforward signalling loop to regulate BATF3 and the transcriptional programme of Hodgkin lymphoma cells. Leukemia, 32. pp. 214-223. ISSN 0887-6924

W

Walker, CR, Hautefort, I, Dalton, JE et al. (7 more authors) (2013) Intestinal intraepithelial lymphocyte-enterocyte crosstalk regulates production of bactericidal angiogenin 4 by Paneth cells upon microbial challenge. PLoS ONE, 8 (12). e84553. ISSN 1932-6203

Worrillow, L, Baskaran, P, Care, MA et al. (9 more authors) (2016) An ultra-deep sequencing strategy to detect sub-clonal TP53 mutations in presentation chronic lymphocytic leukemia cases using multiple polymerases. Oncogene, 35 (40). pp. 5328-5336. ISSN 0950-9232

This list was generated on Tue Nov 20 04:14:50 2018 GMT.