Items where Funder is BREAST CANCER NOW.
Up a level2016MayPR734
Eyre, R., Alférez, D.G., Santiago-Gómez, A. et al. (15 more authors) (2019) Microenvironmental IL1β promotes breast cancer metastatic colonisation in the bone via activation of Wnt signalling. Nature Communications, 10 (1). 5016.
2016MaySP763
Lefley, D., Nutter, F., Brown, H. et al. (7 more authors) (2017) Human specific models for studying ER plus ve and ER- ve breast cancer bone metastasis. In: Clinical and Experimental Metastasis. EACR seed and soil: in vivo models of metastasis conference, 27-29 Nov 2017, Berlin, Germany . Springer Verlag , p. 516.
Lefley, D., Howard, F., Arshad, F. et al. (9 more authors) (2019) Development of clinically relevant in vivo metastasis models using human bone discs and breast cancer patient-derived xenografts. Breast Cancer Research, 21 (1). 130. ISSN 1465-5411
2016NovPCC006
Saleh, L., Ottewell, P.D. orcid.org/0000-0002-4826-0771, Brown, J.E. orcid.org/0000-0003-4960-3032 et al. (6 more authors) (2023) The CDK4/6 inhibitor palbociclib inhibits estrogen-positive and triple negative breast cancer bone metastasis in vivo. Cancers, 15 (8). 2211. ISSN 2072-6694
C47655/A16817
Daniels, S.L., Burghel, G.J., Chambers, P. et al. (9 more authors) (2016) Levels of DNA methylation vary at CpG sites across the BRCA1 promoter, and differ according to triple negative and "BRCA-like" status, in both blood and tumour DNA. PLoS One. ISSN 1932-6203
C5410/A7315.
ABCTB Investigators, EMBRACE, GEMO Study Collaborators et al. (3 more authors) (2017) Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer. Nature Genetics, 49 (12). pp. 1767-1778. ISSN 1061-4036
Daniels, S.L., Burghel, G.J., Chambers, P. et al. (9 more authors) (2016) Levels of DNA methylation vary at CpG sites across the BRCA1 promoter, and differ according to triple negative and "BRCA-like" status, in both blood and tumour DNA. PLoS One. ISSN 1932-6203
Hamdi, Y., Soucy, P., Adoue, V. et al. (93 more authors) (2016) Association of Breast Cancer Risk with Genetic Variants Showing Differential Allelic Expression: Identification of a Novel Breast Cancer Susceptibility Locus at 4q21. Oncotarget, 7. pp. 80140-80163. ISSN 1949-2553
Zeng, C., Guo, X., Long, J. et al. (234 more authors) (2016) Identification of independent association signals and putative functional variants for breast cancer risk through fine-scale mapping of the 12p11 locus. Breast Cancer Research, 18 (1). 64. ISSN 1465-542X
Barrdahl, M. orcid.org/0000-0003-4661-0763, Rudolph, A. orcid.org/0000-0001-7520-2035, Hopper, J.L. et al. (45 more authors) (2017) Gene-environment interactions involving functional variants: results from the Breast Cancer Association Consortium. International Journal of Cancer, 141 (9). pp. 1830-1840. ISSN 0020-7136
C9267/A25152
Escala-Garcia, M., Guo, Q., Dörk, T. et al. (234 more authors) (2019) Genome-wide association study of germline variants and breast cancer-specific mortality. British Journal of Cancer, 120. pp. 647-657. ISSN 0007-0920
Jiang, X, Finucane, HK orcid.org/0000-0003-3864-9828, Schumacher, FR orcid.org/0000-0002-3073-7463 et al. (330 more authors) (2019) Shared heritability and functional enrichment across six solid cancers. Nature Communications, 10. 431. ISSN 2041-1723
Shimelis, H., LaDuca, H., Hu, C. et al. (26 more authors) (2018) Triple-negative breast cancer risk genes identified by multigene hereditary cancer panel testing. JNCI: Journal of the National Cancer Institute, 110 (8). pp. 855-862. ISSN 0027-8874
Day, F.R., Thompson, D.J., Helgason, H. et al. (219 more authors) (2017) Genomic analyses identify hundreds of variants associated with age at menarche and support a role for puberty timing in cancer risk. Nature Genetics, 49 (6). pp. 834-841. ISSN 1061-4036
Wu, L., Shi, W., Long, J. et al. (3 more authors) (2018) A transcriptome-wide association study of 229,000 women identifies new candidate susceptibility genes for breast cancer. Nature Genetics, 50. pp. 968-978. ISSN 1061-4036
NBCS Collaborators, ABCTB Investigators and ConFab/AOCS Investigators (2017) Association analysis identifies 65 new breast cancer risk loci. Nature, 551. pp. 92-94. ISSN 0028-0836
Rudolf, A., Song, M., Brook, M.N. et al. (48 more authors) (2018) Joint associations of a polygenic risk score and environmental risk factors for breast cancer in the Breast Cancer Association Consortium. International Journal of Epidemiology, 47 (2). pp. 526-536. ISSN 0300-5771
Jiao, X., Aravidis, C., Marikkannu, R. et al. (103 more authors) (2017) PHIP - a novel candidate breast cancer susceptibility locus on 6q14.1. Oncotarget, 8. pp. 102769-102782. ISSN 1949-2553
Opstal-van Winden, A.W.J., de Haan, H.G. orcid.org/0000-0003-1126-4776, Hauptmann, M. et al. (27 more authors) (2019) Genetic susceptibility to radiation-induced breast cancer after Hodgkin Lymphoma. Blood, 133 (10). pp. 1130-1139. ISSN 0006-4971
Ferreira, M., Gamazon, E.R., Al-Ejeh, F. et al. (8 more authors) (2019) Genome-wide association and transcriptome studies identify target genes and risk loci for breast cancer. Nature Communications, 10. 1741. ISSN 2041-1723
Kapoor, P.M., Mavaddat, N., Choudhury, P.P. et al. (8 more authors) (2021) Combined associations of a polygenic risk score and classical risk factors with breast cancer risk. JNCI: Journal of the National Cancer Institute, 113 (3). pp. 329-337. ISSN 0027-8874
Fachal, L, Aschard, H, Beesley, J et al. (338 more authors) (2020) Fine-mapping of 150 breast cancer risk regions identifies 191 likely target genes. Nature Genetics, 52 (1). pp. 56-73. ISSN 1061-4036
Park, JY, Choi, JY, Choi, J et al. (90 more authors) (2021) Gene-environment interactions relevant to estrogen and risk of breast cancer: Can gene-environment interactions be detected only among candidate snps from genome-wide association studies? Cancers, 13 (10). 2370. ISSN 2072-6694
Zhang, H, Ahearn, TU, Lecarpentier, J et al. (269 more authors) (2020) Genome-wide association study identifies 32 novel breast cancer susceptibility loci from overall and subtype-specific analyses. Nature Genetics, 52 (6). pp. 572-581. ISSN 1061-4036
Escala-Garcia, M, Abraham, J, Andrulis, IL et al. (142 more authors) (2020) A network analysis to identify mediators of germline-driven differences in breast cancer prognosis. Nature Communications, 11 (1). 312.
Colombo, M., Lopez-Perolio, I., Meeks, H.D. et al. (112 more authors) (2018) The BRCA2 c.68-7T > A variant is not pathogenic: A model for clinical calibration of spliceogenicity. Human Mutation, 39 (5). pp. 729-741. ISSN 1059-7794
Mavaddat, N, Michailidou, K, Dennis, J et al. (266 more authors) (2019) Polygenic Risk Scores for Prediction of Breast Cancer and Breast Cancer Subtypes. The American Journal of Human Genetics, 104 (1). pp. 21-34. ISSN 0002-9297
Dennis, J, Tyrer, JP, Walker, LC et al. (121 more authors) (2022) Rare germline copy number variants (CNVs) and breast cancer risk. Communications Biology, 5. 65. ISSN 2399-3642
Barrdahl, M. orcid.org/0000-0003-4661-0763, Rudolph, A. orcid.org/0000-0001-7520-2035, Hopper, J.L. et al. (45 more authors) (2017) Gene-environment interactions involving functional variants: results from the Breast Cancer Association Consortium. International Journal of Cancer, 141 (9). pp. 1830-1840. ISSN 0020-7136
CA114
Lefley, D., Howard, F., Arshad, F. et al. (9 more authors) (2019) Development of clinically relevant in vivo metastasis models using human bone discs and breast cancer patient-derived xenografts. Breast Cancer Research, 21 (1). 130. ISSN 1465-5411
CA136
Lefley, D., Nutter, F., Brown, H. et al. (7 more authors) (2017) Human specific models for studying ER plus ve and ER- ve breast cancer bone metastasis. In: Clinical and Experimental Metastasis. EACR seed and soil: in vivo models of metastasis conference, 27-29 Nov 2017, Berlin, Germany . Springer Verlag , p. 516.
CA142
Eyre, R., Alférez, D.G., Santiago-Gómez, A. et al. (15 more authors) (2019) Microenvironmental IL1β promotes breast cancer metastatic colonisation in the bone via activation of Wnt signalling. Nature Communications, 10 (1). 5016.
Dr Simon Vincent
Colombo, M., Lopez-Perolio, I., Meeks, H.D. et al. (112 more authors) (2018) The BRCA2 c.68-7T > A variant is not pathogenic: A model for clinical calibration of spliceogenicity. Human Mutation, 39 (5). pp. 729-741. ISSN 1059-7794
MR/P000096/1
Eyre, R., Alférez, D.G., Santiago-Gómez, A. et al. (15 more authors) (2019) Microenvironmental IL1β promotes breast cancer metastatic colonisation in the bone via activation of Wnt signalling. Nature Communications, 10 (1). 5016.
None
Lefley, D., Howard, F., Arshad, F. et al. (9 more authors) (2019) Development of clinically relevant in vivo metastasis models using human bone discs and breast cancer patient-derived xenografts. Breast Cancer Research, 21 (1). 130. ISSN 1465-5411
R116428
Eyre, R., Alférez, D.G., Santiago-Gómez, A. et al. (15 more authors) (2019) Microenvironmental IL1β promotes breast cancer metastatic colonisation in the bone via activation of Wnt signalling. Nature Communications, 10 (1). 5016.
R120127
Eyre, R., Alférez, D.G., Santiago-Gómez, A. et al. (15 more authors) (2019) Microenvironmental IL1β promotes breast cancer metastatic colonisation in the bone via activation of Wnt signalling. Nature Communications, 10 (1). 5016.
S299
Daniels, S.L., Burghel, G.J., Chambers, P. et al. (9 more authors) (2016) Levels of DNA methylation vary at CpG sites across the BRCA1 promoter, and differ according to triple negative and "BRCA-like" status, in both blood and tumour DNA. PLoS One. ISSN 1932-6203
Hamdi, Y., Soucy, P., Adoue, V. et al. (93 more authors) (2016) Association of Breast Cancer Risk with Genetic Variants Showing Differential Allelic Expression: Identification of a Novel Breast Cancer Susceptibility Locus at 4q21. Oncotarget, 7. pp. 80140-80163. ISSN 1949-2553
Zeng, C., Guo, X., Long, J. et al. (234 more authors) (2016) Identification of independent association signals and putative functional variants for breast cancer risk through fine-scale mapping of the 12p11 locus. Breast Cancer Research, 18 (1). 64. ISSN 1465-542X
Barrdahl, M. orcid.org/0000-0003-4661-0763, Rudolph, A. orcid.org/0000-0001-7520-2035, Hopper, J.L. et al. (45 more authors) (2017) Gene-environment interactions involving functional variants: results from the Breast Cancer Association Consortium. International Journal of Cancer, 141 (9). pp. 1830-1840. ISSN 0020-7136
TB2009SHEF
Daniels, S.L., Burghel, G.J., Chambers, P. et al. (9 more authors) (2016) Levels of DNA methylation vary at CpG sites across the BRCA1 promoter, and differ according to triple negative and "BRCA-like" status, in both blood and tumour DNA. PLoS One. ISSN 1932-6203
Hamdi, Y., Soucy, P., Adoue, V. et al. (93 more authors) (2016) Association of Breast Cancer Risk with Genetic Variants Showing Differential Allelic Expression: Identification of a Novel Breast Cancer Susceptibility Locus at 4q21. Oncotarget, 7. pp. 80140-80163. ISSN 1949-2553
TB2017SHEF
Wu, L., Shi, W., Long, J. et al. (3 more authors) (2018) A transcriptome-wide association study of 229,000 women identifies new candidate susceptibility genes for breast cancer. Nature Genetics, 50. pp. 968-978. ISSN 1061-4036
NBCS Collaborators, ABCTB Investigators and ConFab/AOCS Investigators (2017) Association analysis identifies 65 new breast cancer risk loci. Nature, 551. pp. 92-94. ISSN 0028-0836
Rudolf, A., Song, M., Brook, M.N. et al. (48 more authors) (2018) Joint associations of a polygenic risk score and environmental risk factors for breast cancer in the Breast Cancer Association Consortium. International Journal of Epidemiology, 47 (2). pp. 526-536. ISSN 0300-5771
Jiao, X., Aravidis, C., Marikkannu, R. et al. (103 more authors) (2017) PHIP - a novel candidate breast cancer susceptibility locus on 6q14.1. Oncotarget, 8. pp. 102769-102782. ISSN 1949-2553
Opstal-van Winden, A.W.J., de Haan, H.G. orcid.org/0000-0003-1126-4776, Hauptmann, M. et al. (27 more authors) (2019) Genetic susceptibility to radiation-induced breast cancer after Hodgkin Lymphoma. Blood, 133 (10). pp. 1130-1139. ISSN 0006-4971
Ferreira, M., Gamazon, E.R., Al-Ejeh, F. et al. (8 more authors) (2019) Genome-wide association and transcriptome studies identify target genes and risk loci for breast cancer. Nature Communications, 10. 1741. ISSN 2041-1723
Colombo, M., Lopez-Perolio, I., Meeks, H.D. et al. (112 more authors) (2018) The BRCA2 c.68-7T > A variant is not pathogenic: A model for clinical calibration of spliceogenicity. Human Mutation, 39 (5). pp. 729-741. ISSN 1059-7794
Mavaddat, N, Michailidou, K, Dennis, J et al. (266 more authors) (2019) Polygenic Risk Scores for Prediction of Breast Cancer and Breast Cancer Subtypes. The American Journal of Human Genetics, 104 (1). pp. 21-34. ISSN 0002-9297
Dennis, J, Tyrer, JP, Walker, LC et al. (121 more authors) (2022) Rare germline copy number variants (CNVs) and breast cancer risk. Communications Biology, 5. 65. ISSN 2399-3642
TB2018SHEF
Mavaddat, N, Michailidou, K, Dennis, J et al. (266 more authors) (2019) Polygenic Risk Scores for Prediction of Breast Cancer and Breast Cancer Subtypes. The American Journal of Human Genetics, 104 (1). pp. 21-34. ISSN 0002-9297
Dennis, J, Tyrer, JP, Walker, LC et al. (121 more authors) (2022) Rare germline copy number variants (CNVs) and breast cancer risk. Communications Biology, 5. 65. ISSN 2399-3642
TB2O19BAR
Johnson, N, Maguire, S, Morra, A et al. (145 more authors) (2021) CYP3A7*1C allele: linking premenopausal oestrone and progesterone levels with risk of hormone receptor-positive breast cancers. British Journal of Cancer, 124 (4). pp. 842-854. ISSN 0007-0920
Kapoor, P.M., Mavaddat, N., Choudhury, P.P. et al. (8 more authors) (2021) Combined associations of a polygenic risk score and classical risk factors with breast cancer risk. JNCI: Journal of the National Cancer Institute, 113 (3). pp. 329-337. ISSN 0027-8874
Fachal, L, Aschard, H, Beesley, J et al. (338 more authors) (2020) Fine-mapping of 150 breast cancer risk regions identifies 191 likely target genes. Nature Genetics, 52 (1). pp. 56-73. ISSN 1061-4036
Park, JY, Choi, JY, Choi, J et al. (90 more authors) (2021) Gene-environment interactions relevant to estrogen and risk of breast cancer: Can gene-environment interactions be detected only among candidate snps from genome-wide association studies? Cancers, 13 (10). 2370. ISSN 2072-6694
Zhang, H, Ahearn, TU, Lecarpentier, J et al. (269 more authors) (2020) Genome-wide association study identifies 32 novel breast cancer susceptibility loci from overall and subtype-specific analyses. Nature Genetics, 52 (6). pp. 572-581. ISSN 1061-4036
Escala-Garcia, M, Abraham, J, Andrulis, IL et al. (142 more authors) (2020) A network analysis to identify mediators of germline-driven differences in breast cancer prognosis. Nature Communications, 11 (1). 312.
Dennis, J, Tyrer, JP, Walker, LC et al. (121 more authors) (2022) Rare germline copy number variants (CNVs) and breast cancer risk. Communications Biology, 5. 65. ISSN 2399-3642