Foster, J.A., Parker, R.M., Belenguer, A.M. et al. (4 more authors) (2015) Differentially Addressable Cavities within Metal-Organic Cage-Cross-Linked Polymeric Hydrogels. Journal of the American Chemical Society, 137 (30). pp. 9722-9729. ISSN 0002-7863
Abstract
Here we report a new class of hydrogels formed by polymers that are cross-linked through subcomponent self-assembled metal–organic cages. Selective encapsulation of guest molecules within the cages creates two distinct internal phases within the hydrogel, which allows for contrasting release profiles of related molecules depending on their aptitude for encapsulation within the cages. The hydrogels were fabricated into microparticles via a droplet-based microfluidic approach and proved responsive to a variety of stimuli, including acid and competing amine or aldehyde subcomponents, allowing for the triggered release of cargo.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © 2015 American Chemical Society. This is an author produced version of a paper subsequently published in Journal of the American Chemical Society. Uploaded in accordance with the publisher's self-archiving policy. |
Dates: |
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Institution: | The University of Sheffield |
Academic Units: | The University of Sheffield > Faculty of Science (Sheffield) > Department of Chemistry (Sheffield) |
Depositing User: | Symplectic Sheffield |
Date Deposited: | 13 Apr 2016 15:12 |
Last Modified: | 05 Nov 2017 15:59 |
Published Version: | http://dx.doi.org/10.1021/jacs.5b05507 |
Status: | Published |
Publisher: | American Chemical Society |
Refereed: | Yes |
Identification Number: | 10.1021/jacs.5b05507 |
Related URLs: | |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:98069 |