Parmar, MJ, De Marcos Lousa, C, Muench, SP et al. (2 more authors) (2016) Artificial membranes for membrane protein purification, functionality and structure studies. Biochemical Society Transactions, 44 (3). pp. 877-882. ISSN 0300-5127
Abstract
Membrane proteins represent one of the most important targets for pharmaceutical companies. Unfortunately, technical limitations have long been a major hindrance in our understanding of the function and structure of such proteins. Recent years have seen the refinement of classical approaches and the emergence of new technologies that have resulted in a significant step forward in the field of membrane protein research. This review summarises some of the current techniques used for studying membrane proteins, with overall advantages and drawbacks for each method.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © 2016 The Author(s). published by Portland Press Limited on behalf of the Biochemical Society. This is an author produced version of a paper published in Biochemical Society Transactions. Uploaded in accordance with the publisher's self-archiving policy. |
Keywords: | Membrane proteins; Nanodiscs; SMALPs; Bicelle; LCP; SLB; BLM; Lipodisq |
Dates: |
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Institution: | The University of Leeds |
Academic Units: | The University of Leeds > Faculty of Biological Sciences (Leeds) > School of Biomedical Sciences (Leeds) |
Funding Information: | Funder Grant number Royal Society WM120073 Wellcome Trust 091322/Z/10/Z |
Depositing User: | Symplectic Publications |
Date Deposited: | 08 Apr 2016 10:05 |
Last Modified: | 01 Jul 2017 22:51 |
Published Version: | http://dx.doi.org/10.1042/BST20160054 |
Status: | Published |
Publisher: | Portland Press |
Identification Number: | 10.1042/BST20160054 |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:98061 |