Flight, L. orcid.org/0000-0002-9569-8290 and Julious, S.A. (2016) Practical guide to sample size calculations: an introduction. Pharmaceutical Statistics , 15 (1). pp. 68-74. ISSN 1539-1604
Abstract
A sample size justification is a vital step when designing any trial. However, estimating the number of participants required to give a meaningful result is not always straightforward. A number of components are required to facilitate a suitable sample size calculation. In this paper, the general steps are summarised for conducting sample size calculations with practical advice and guidance on how to utilise the app SampSize.
Metadata
Item Type: | Article |
---|---|
Authors/Creators: |
|
Copyright, Publisher and Additional Information: | © 2015 John Wiley & Sons, Ltd. This is an author produced version of a paper subsequently published in Pharmaceutical Statistics. Uploaded in accordance with the publisher's self-archiving policy. |
Keywords: | sample size; superiority; non-inferiority; equivalence; power; clinical trials |
Dates: |
|
Institution: | The University of Sheffield |
Academic Units: | The University of Sheffield > Faculty of Medicine, Dentistry and Health (Sheffield) > School of Health and Related Research (Sheffield) > ScHARR - Sheffield Centre for Health and Related Research |
Depositing User: | Symplectic Sheffield |
Date Deposited: | 01 Apr 2016 10:31 |
Last Modified: | 23 Nov 2016 06:28 |
Published Version: | http://dx.doi.org/10.1002/pst.1709 |
Status: | Published |
Publisher: | Wiley |
Refereed: | Yes |
Identification Number: | 10.1002/pst.1709 |
Related URLs: | |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:97115 |