Apoptosis and failure of checkpoint kinase 1 activation in human induced pluripotent stem cells under replication stress

Desmarais, J.A., Unger, C., Damjanov, I. et al. (2 more authors) (2016) Apoptosis and failure of checkpoint kinase 1 activation in human induced pluripotent stem cells under replication stress. Stem Cell Research & Therapy, 7 (1). ARTN 17.

Abstract

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Authors/Creators:
  • Desmarais, J.A.
  • Unger, C.
  • Damjanov, I.
  • Meuth, M.
  • Andrews, P.
Copyright, Publisher and Additional Information: © 2016 Desmarais et al. Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
Keywords: Induced pluripotent stem cells; Integration-free reprogramming; Checkpoint kinase 1; Apoptosis; Replication stress; Ataxia telangiectasia and rad3-related; Ataxia telangiectasia mutated; Genomic instability
Dates:
  • Published: 25 January 2016
  • Accepted: 12 January 2016
  • Published (online): 25 January 2016
Institution: The University of Sheffield
Academic Units: The University of Sheffield > Faculty of Medicine, Dentistry and Health (Sheffield) > School of Medicine (Sheffield) > Division of Genomic Medicine (Sheffield) > Department of Oncology (Sheffield)
The University of Sheffield > Faculty of Science (Sheffield) > School of Biological Sciences (Sheffield) > Department of Biomedical Science (Sheffield)
The University of Sheffield > Sheffield Teaching Hospitals
Depositing User: Symplectic Sheffield
Date Deposited: 11 Jul 2016 09:39
Last Modified: 11 Jul 2016 09:46
Published Version: http://dx.doi.org/10.1186/s13287-016-0279-2
Status: Published
Publisher: Biomed Central
Refereed: Yes
Identification Number: https://doi.org/10.1186/s13287-016-0279-2
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