Landscape of activating cancer mutations in FGFR kinases and their differential responses to inhibitors in clinical use

Patani, H, Bunney, TD, Thiyagarajan, N et al. (14 more authors) (2016) Landscape of activating cancer mutations in FGFR kinases and their differential responses to inhibitors in clinical use. Oncotarget, 7 (17). pp. 24252-24268. ISSN 1949-2553

Abstract

Metadata

Authors/Creators:
  • Patani, H
  • Bunney, TD
  • Thiyagarajan, N
  • Norman, RA
  • Ogg, D
  • Breed, J
  • Ashford, P
  • Potterton, A
  • Edwards, M
  • Williams, SV
  • Thomson, GS
  • Pang, CSM
  • Knowles, MA
  • Breeze, AL
  • Orengo, C
  • Phillips, C
  • Katan, M
Copyright, Publisher and Additional Information: © 2016 The Authors. This is an open access article under the terms of the Creative Commons Attribution License (CC-BY 3.0)
Keywords: precision medicine; cancer mutations; receptor tyrosine kinases; small molecule inhibitors; resistance
Dates:
  • Published: 16 March 2016
  • Accepted: 28 February 2016
Institution: The University of Leeds
Academic Units: The University of Leeds > Faculty of Biological Sciences (Leeds)
The University of Leeds > Faculty of Medicine and Health (Leeds) > Institute of Molecular Medicine (LIMM) (Leeds) > Section of Experimental Oncology (Leeds)
The University of Leeds > Faculty of Medicine and Health (Leeds) > School of Medicine (Leeds) > Leeds Institute of Cancer and Pathology (LICAP) > Section of Experimental Oncology (Leeds)
Funding Information:
FunderGrant number
Yorkshire Cancer ResearchL367
Yorkshire Cancer ResearchL376PA
Depositing User: Symplectic Publications
Date Deposited: 09 Mar 2016 14:14
Last Modified: 12 Apr 2017 17:41
Published Version: https://dx.doi.org/10.18632/oncotarget.8132
Status: Published
Publisher: Impact Journals
Identification Number: https://doi.org/10.18632/oncotarget.8132

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