Gotham, V.J., Hobbs, M.C., Burgin, R. et al. (3 more authors) (2016) Synthesis and activity of a novel inhibitor of nonsense-mediated mRNA decay. Organic & Biomolecular Chemistry, 14 (5). pp. 1559-1563. ISSN 1477-0520
Abstract
During efforts to prepare the known compound , a new tetracyclic compound, called , was prepared in six steps. This compound was found to have good activity as an inhibitor of nonsense-mediated mRNA decay.
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Copyright, Publisher and Additional Information: | This article is licensed under a Creative Commons Attribution 3.0 Unported Licence (http://creativecommons.org/licenses/by/3.0/). | ||||||||||||||
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Institution: | The University of Sheffield | ||||||||||||||
Academic Units: | The University of Sheffield > Faculty of Science (Sheffield) > School of Biosciences (Sheffield) > Department of Biomedical Science (Sheffield) The University of Sheffield > Faculty of Science (Sheffield) > Department of Chemistry (Sheffield) |
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Depositing User: | Symplectic Sheffield | ||||||||||||||
Date Deposited: | 18 Feb 2016 09:24 | ||||||||||||||
Last Modified: | 18 Feb 2016 09:24 | ||||||||||||||
Published Version: | https://dx.doi.org/10.1039/c5ob02482j | ||||||||||||||
Status: | Published | ||||||||||||||
Publisher: | Royal Society of Chemistry | ||||||||||||||
Refereed: | Yes | ||||||||||||||
Identification Number: | https://doi.org/10.1039/c5ob02482j | ||||||||||||||
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