Maiden, T.M.M., Swanson, S., Procopiou, P.A. et al. (1 more author) (2015) A Mild and Regioselective Route to Functionalized Quinazolines. Chemistry - A European Journal, 21 (41). pp. 14342-14346. ISSN 0947-6539
Abstract
A Rh-catalyzed ortho-amidation cyclocondensation sequence gave a range of 4-aminoquinazolines in high yield. The method features a remarkably mild C(sp<sup>2</sup>)-H activation step and can be exploited to rapidly access compounds with established biological activity.
Metadata
| Authors/Creators: |
|
|---|---|
| Copyright, Publisher and Additional Information: | © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. |
| Keywords: | amidation; cyclization; homogeneous catalysis; oxazolines; quinazolines |
| Dates: |
|
| Institution: | The University of Sheffield |
| Academic Units: | The University of Sheffield > Faculty of Science (Sheffield) > Department of Chemistry (Sheffield) |
| Depositing User: | Symplectic Sheffield |
| Date Deposited: | 17 Feb 2016 15:49 |
| Last Modified: | 17 Feb 2016 15:49 |
| Published Version: | http://dx.doi.org/10.1002/chem.201502891 |
| Status: | Published |
| Publisher: | Wiley-VCH Verlag |
| Identification Number: | https://doi.org/10.1002/chem.201502891 |
Download not available
A full text copy of this item is not currently available from White Rose Research Online
CORE (COnnecting REpositories)
CORE (COnnecting REpositories)