Multi-omic measurement of mutually exclusive loss-of-function enriches for candidate synthetic lethal gene pairs.

Wappett, M., Dulak, A., Yang, Z.R. et al. (3 more authors) (2016) Multi-omic measurement of mutually exclusive loss-of-function enriches for candidate synthetic lethal gene pairs. BMC Genomics, 17. 65. ISSN 1471-2164

Abstract

Metadata

Authors/Creators:
  • Wappett, M.
  • Dulak, A.
  • Yang, Z.R.
  • Al-Watban, A.
  • Bradford, J.R.
  • Dry, J.R.
Copyright, Publisher and Additional Information: © 2016 Wappett et al. Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
Keywords: Bioinformatics; Transcriptomics; Synthetic lethality; R; Epigenetics; Functional genomics; Cancer Cell line
Dates:
  • Published: 16 January 2016
  • Accepted: 6 January 2016
Institution: The University of Sheffield
Academic Units: The University of Sheffield > Faculty of Medicine, Dentistry and Health (Sheffield) > School of Medicine (Sheffield) > Division of Genomic Medicine (Sheffield) > Department of Oncology (Sheffield)
The University of Sheffield > Sheffield Teaching Hospitals
Depositing User: Symplectic Sheffield
Date Deposited: 21 Jan 2016 11:18
Last Modified: 21 Jan 2016 11:18
Published Version: http://dx.doi.org/10.1186/s12864-016-2375-1
Status: Published
Publisher: BioMed Central
Refereed: Yes
Identification Number: https://doi.org/10.1186/s12864-016-2375-1
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