McCullagh, B.N., Costello, C.M., Li, L. et al. (9 more authors) (2015) Elevated plasma CXCL12 alpha is associated with a poorer prognosis in pulmonary arterial hypertension. PLoS ONE, 10 (4). e0123709. ISSN 1932-6203
Abstract
Recent work in preclinical models suggests that signalling via the pro-angiogenic and proinflammatory cytokine, CXCL12 (SDF-1), plays an important pathogenic role in pulmonary hypertension (PH). The objective of this study was to establish whether circulating concentrations of CXCL12α were elevated in patients with PAH and related to mortality
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © 2015. The Author(s). This is an Open Access article distributed under the terms of the Creative Commons Attribution Licence (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
Dates: |
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Institution: | The University of Sheffield |
Academic Units: | The University of Sheffield > Faculty of Medicine, Dentistry and Health (Sheffield) > The Medical School (Sheffield) > Department of Cardiovascular Science |
Depositing User: | Symplectic Sheffield |
Date Deposited: | 29 Jul 2015 10:21 |
Last Modified: | 29 Jul 2015 10:21 |
Published Version: | http://dx.doi.org/10.1371/journal.pone.0123709 |
Status: | Published |
Publisher: | Public Library of Science |
Refereed: | Yes |
Identification Number: | 10.1371/journal.pone.0123709 |
Related URLs: | |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:88261 |