Pharmacological inactivation of Skp2 SCF ubiquitin ligase restricts cancer stem cell traits and cancer progression

Chan, CH, Morrow, JK, Li, CF et al. (11 more authors) (2013) Pharmacological inactivation of Skp2 SCF ubiquitin ligase restricts cancer stem cell traits and cancer progression. Cell, 154 (3). 556 - 568. ISSN 0092-8674

Abstract

Metadata

Authors/Creators:
  • Chan, CH
  • Morrow, JK
  • Li, CF
  • Gao, Y
  • Jin, G
  • Moten, A
  • Stagg, LJ
  • Ladbury, JE
  • Cai, Z
  • Xu, D
  • Logothetis, CJ
  • Hung, MC
  • Zhang, S
  • Lin, HK
Keywords: Animals; Antineoplastic Agents; Disease Models, Animal; Drug Discovery; Drug Screening Assays, Antitumor; Genes, p53; Glycolysis; Humans; Mice; Mice, Nude; Models, Molecular; Multienzyme Complexes; Neoplasm Transplantation; Neoplasms; Neoplastic Stem Cells; S-Phase Kinase-Associated Proteins; Small Molecule Libraries; Structure-Activity Relationship; Transplantation, Heterologous; Ubiquitin-Protein Ligases
Dates:
  • Published: 1 August 2013
Institution: The University of Leeds
Academic Units: The University of Leeds > Faculty of Biological Sciences (Leeds) > School of Molecular and Cellular Biology (Leeds)
Depositing User: Symplectic Publications
Date Deposited: 11 Nov 2015 13:47
Last Modified: 11 Nov 2015 13:55
Published Version: http://dx.doi.org/10.1016/j.cell.2013.06.048
Status: Published
Publisher: Elsevier
Identification Number: https://doi.org/10.1016/j.cell.2013.06.048
Related URLs:

Download not available

A full text copy of this item is not currently available from White Rose Research Online

Share / Export

Statistics