Discovery and characterization of novel selective inhibitors of carbonic anhydrase IX

Dudutiene, V, Matuliene, J, Smirnov, A et al. (31 more authors) (2014) Discovery and characterization of novel selective inhibitors of carbonic anhydrase IX. Journal of Medicinal Chemistry, 57 (22). 9435 - 9446. ISSN 0022-2623

Abstract

Metadata

Authors/Creators:
  • Dudutiene, V
  • Matuliene, J
  • Smirnov, A
  • Timm, DD
  • Zubriene, A
  • Baranauskiene, L
  • Morkunaite, V
  • Smirnoviene, J
  • Michailoviene, V
  • Juozapaitiene, V
  • Mickevičiute, A
  • Kazokaite, J
  • Bakšyte, S
  • Kasiliauskaite, A
  • Jachno, J
  • Revuckiene, J
  • Kišonaite, M
  • Pilipuityte, V
  • Ivanauskaite, E
  • Milinavičiute, G
  • Smirnovas, V
  • Petrikaite, V
  • Kairys, V
  • Petrauskas, V
  • Norvaišas, P
  • Linge, D
  • Gibieža, P
  • Čapkauskaite, E
  • Zakšauskas, A
  • Kazlauskas, E
  • Manakova, E
  • Gražulis, S
  • Ladbury, JE
  • Matulis, D
Keywords: Benzene; Calorimetry; Carbon Dioxide; Carbonic Anhydrase IV; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Catalysis; Catalytic Domain; Crystallization; Crystallography, X-Ray; Drug Design; Humans; Hydrogen-Ion Concentration; Kinetics; Neoplasms; Protein Binding; Protein Conformation; Recombinant Proteins; Sulfonamides; Thermodynamics
Dates:
  • Published: 30 October 2014
Institution: The University of Leeds
Academic Units: The University of Leeds > Faculty of Biological Sciences (Leeds) > Faculty of Biological Sciences Office (Leeds)
Depositing User: Symplectic Publications
Date Deposited: 22 Jul 2015 13:28
Last Modified: 03 Nov 2016 08:43
Published Version: http://dx.doi.org/10.1021/jm501003k
Status: Published
Publisher: American Chemical Society
Identification Number: https://doi.org/10.1021/jm501003k
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