The Effect of Mutations on Drug Sensitivity and Kinase Activity of Fibroblast Growth Factor Receptors: A Combined Experimental and Theoretical Study

Bunney, TD, Wan, S, Thiyagarajan, N et al. (8 more authors) (2015) The Effect of Mutations on Drug Sensitivity and Kinase Activity of Fibroblast Growth Factor Receptors: A Combined Experimental and Theoretical Study. EBiomedicine, 2 (3). 194 - 204.

Abstract

Metadata

Authors/Creators:
  • Bunney, TD
  • Wan, S
  • Thiyagarajan, N
  • Sutto, L
  • Williams, SV
  • Ashford, P
  • Koss, H
  • Knowles, MA
  • Gervasio, FL
  • Coveney, PV
  • Katan, M
Copyright, Publisher and Additional Information: © 2015 The Authors. Published by Elsevier B.V. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
Keywords: Cancer; FGFR; Clinical inhibitors; Resistance mutations
Dates:
  • Published: March 2015
  • Accepted: 13 February 2015
Institution: The University of Leeds
Academic Units: The University of Leeds > Faculty of Medicine and Health (Leeds) > Institute of Molecular Medicine (LIMM) (Leeds) > Section of Experimental Oncology (Leeds)
The University of Leeds > Faculty of Medicine and Health (Leeds) > School of Medicine (Leeds) > Leeds Institute of Cancer and Pathology (LICAP) > Section of Experimental Oncology (Leeds)
Depositing User: Symplectic Publications
Date Deposited: 14 Oct 2015 15:32
Last Modified: 16 Jan 2018 05:44
Published Version: http://dx.doi.org/10.1016/j.ebiom.2015.02.009
Status: Published
Publisher: Elsevier
Identification Number: https://doi.org/10.1016/j.ebiom.2015.02.009

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