Parallel RNA interference screens identify EGFR activation as an escape mechanism in FGFR3-mutant cancer.

Herrera-Abreu, MT, Pearson, A, Campbell, J et al. (4 more authors) (2013) Parallel RNA interference screens identify EGFR activation as an escape mechanism in FGFR3-mutant cancer. Cancer Discovery, 3 (9). 1058 - 1071. ISSN 2159-8274

Abstract

Metadata

Authors/Creators:
  • Herrera-Abreu, MT
  • Pearson, A
  • Campbell, J
  • Shnyder, SD
  • Knowles, MA
  • Ashworth, A
  • Turner, NC
Copyright, Publisher and Additional Information: © 2013 American Association for Cancer Research. This is an author produced version of a paper published in Cancer Discovery. Uploaded in accordance with the publisher's self-archiving policy.
Keywords: Animals; Cell Line, Tumor; Heterografts; High-Throughput Screening Assays; Humans; MAP Kinase Signaling System; Mice; Neoplasm Transplantation; Neoplasms; Protein Kinase Inhibitors; Pyrimidines; Quinazolines; RNA Interference; RNA, Small Interfering; Receptor, Epidermal Growth Factor; Receptor, Fibroblast Growth Factor, Type 3; Signal Transduction; Thiazoles
Dates:
  • Published: September 2013
Institution: The University of Leeds
Academic Units: The University of Leeds > Faculty of Medicine and Health (Leeds) > Institute of Molecular Medicine (LIMM) (Leeds) > Section of Experimental Oncology (Leeds)
The University of Leeds > Faculty of Medicine and Health (Leeds) > School of Medicine (Leeds) > Leeds Institute of Cancer and Pathology (LICAP) > Section of Experimental Oncology (Leeds)
Depositing User: Symplectic Publications
Date Deposited: 09 Nov 2015 16:52
Last Modified: 03 Nov 2017 04:16
Published Version: http://dx.doi.org/10.1158/2159-8290.CD-12-0569
Status: Published
Publisher: American Association for Cancer Research
Identification Number: https://doi.org/10.1158/2159-8290.CD-12-0569
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