Evidence of NLRP3-inflammasome activation in rheumatoid arthritis (RA); genetic variants within the NLRP3-inflammasome complex in relation to susceptibility to RA and response to anti-TNF treatment.

Mathews, RJ, Robinson, JI orcid.org/0000-0001-5425-7520, Battellino, M et al. (17 more authors) (2014) Evidence of NLRP3-inflammasome activation in rheumatoid arthritis (RA); genetic variants within the NLRP3-inflammasome complex in relation to susceptibility to RA and response to anti-TNF treatment. Annals of the Rheumatic Diseases, 73 (6). pp. 1202-1210. ISSN 0003-4967

Abstract

Metadata

Authors/Creators:
Keywords: Anti-TNF; Inflammation; Rheumatoid Arthritis; Treatment; Adult; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; CARD Signaling Adaptor Proteins; Carrier Proteins; Case-Control Studies; Caspase 1; Cytoskeletal Proteins; Female; Gene Expression Profiling; Genetic Predisposition to Disease; Genotype; Humans; Inflammasomes; Linear Models; Male; Middle Aged; Multivariate Analysis; Neoplasm Proteins; Polymorphism, Single Nucleotide; RNA, Messenger; Tumor Necrosis Factor-alpha
Dates:
  • Published: June 2014
  • Accepted: 14 April 2013
  • Published (online): 17 May 2013
Institution: The University of Leeds
Academic Units: The University of Leeds > Faculty of Medicine and Health (Leeds) > School of Medicine (Leeds) > Leeds Institute of Cardiovascular and Metabolic Medicine (LICAMM) > Discovery & Translational Science Dept (Leeds)
The University of Leeds > Faculty of Medicine and Health (Leeds) > Institute of Molecular Medicine (LIMM) (Leeds) > Section of Epidemiology and Biostatistics (Leeds)
The University of Leeds > Faculty of Medicine and Health (Leeds) > School of Medicine (Leeds) > Leeds Institute of Cancer and Pathology (LICAP) > Infection and Immunity (Leeds)
The University of Leeds > Faculty of Medicine and Health (Leeds) > School of Medicine (Leeds) > Institute of Rheumatology & Musculoskeletal Medicine (LIRMM) (Leeds) > Clinical Musculoskeletal Medicine (LIRMM) (Leeds)
The University of Leeds > Faculty of Medicine and Health (Leeds) > School of Medicine (Leeds) > Institute of Rheumatology & Musculoskeletal Medicine (LIRMM) (Leeds) > Experimental Musculoskeletal Medicine (Leeds)
The University of Leeds > Faculty of Medicine and Health (Leeds) > School of Medicine (Leeds) > Institute of Rheumatology & Musculoskeletal Medicine (LIRMM) (Leeds) > Inflammatory Arthritis (Leeds)
Funding Information:
FunderGrant number
Leeds Teaching Hospitals Charitable FoundationR&D PP 1107
Depositing User: Symplectic Publications
Date Deposited: 21 Oct 2015 14:24
Last Modified: 29 Jan 2019 12:42
Status: Published
Publisher: BMJ Publishing Group
Identification Number: https://doi.org/10.1136/annrheumdis-2013-203276
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