Pyridine-3-carboxamide-6-yl-ureas as novel inhibitors of bacterial DNA gyrase: Structure based design, synthesis, SAR and antimicrobial activity

Yule, IA, Czaplewski, LG, Pommier, S et al. (3 more authors) (2014) Pyridine-3-carboxamide-6-yl-ureas as novel inhibitors of bacterial DNA gyrase: Structure based design, synthesis, SAR and antimicrobial activity. European Journal of Medicinal Chemistry, 86. 31 - 38. ISSN 0223-5234

Abstract

Metadata

Item Type: Article
Authors/Creators:
  • Yule, IA
  • Czaplewski, LG
  • Pommier, S
  • Davies, DT
  • Narramore, SK
  • Fishwick, CWG
Copyright, Publisher and Additional Information:

(c) 2014, Elsevier. NOTICE: this is the author’s version of a work that was accepted for publication in the European Journal of Medicinal Chemistry. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in European Journal of Medicinal Chemistry, 86, 2014, 10.1016/j.ejmech.2014.08.025

Keywords: Bacterial resistance; DNA gyrase; pyridine-3-carboxamide; molecular modelling
Dates:
  • Published: 30 October 2014
Institution: The University of Leeds
Academic Units: The University of Leeds > Faculty of Engineering & Physical Sciences (Leeds) > School of Chemistry (Leeds)
Depositing User: Symplectic Publications
Date Deposited: 26 Mar 2015 12:33
Last Modified: 21 Apr 2015 05:37
Published Version: http://dx.doi.org/10.1016/j.ejmech.2014.08.025
Status: Published
Publisher: Elsevier
Identification Number: 10.1016/j.ejmech.2014.08.025
Open Archives Initiative ID (OAI ID):

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