Kidambi, A, Biglands, J, Higgins, D et al. (9 more authors) (2014) Susceptibility-weighted cardiovascular magnetic resonance in comparison to T2 and T2 star imaging for detection of intramyocardial hemorrhage following acute myocardial infarction at 3 Tesla. Journal of Cardiovascular Magnetic Resonance, 16. 1. 86 - 86. ISSN 1097-6647
Abstract
BACKGROUND:Intramyocardial hemorrhage (IMH) identified by cardiovascular magnetic resonance (CMR) is an established prognostic marker following acute myocardial infarction (AMI). Detection of IMH by T2-weighted or T2 star CMR can be limited by long breath hold times and sensitivity to artefacts, especially at 3T. We compared the image quality and diagnostic ability of susceptibility-weighted magnetic resonance imaging (SW MRI) with T2-weighted and T2 star CMR to detect IMH at 3T.METHODS:Forty-nine patients (42 males; mean age 58years, range 35-76) underwent 3T cardiovascular magnetic resonance (CMR) 2days following re-perfused AMI. T2-weighted, T2 star and SW MRI images were obtained. Signal and contrast measurements were compared between the three methods and diagnostic accuracy of SW MRI was assessed against T2w images by 2 independent, blinded observers. Image quality was rated on a 4-point scale from 1 (unusable) to 4 (excellent).RESULTS:Of 49 patients, IMH was detected in 20 (41%) by SW MRI, 21 (43%) by T2-weighted and 17 (34%) by T2 star imaging (p=ns). Compared to T2-weighted imaging, SW MRI had sensitivity of 93% and specificity of 86%. SW MRI had similar inter-observer reliability to T2-weighted imaging (kappa=0.90 and kappa=0.88 respectively); both had higher reliability than T2 star (kappa=0.53). Breath hold times were shorter for SW MRI (4seconds vs. 16seconds) with improved image quality rating (3.8+/-0.4, 3.3+/-1.0, 2.8+/-1.1 respectively; p<0.01).CONCLUSIONS:SW MRI is an accurate and reproducible way to detect IMH at 3T. The technique offers considerably shorter breath hold times than T2-weighted and T2 star imaging, and higher image quality scores.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © 2014 Kidambi et al.; licensee BioMed Central. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. |
Dates: |
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Institution: | The University of Leeds |
Academic Units: | The University of Leeds > Faculty of Medicine and Health (Leeds) > School of Medicine (Leeds) |
Depositing User: | Symplectic Publications |
Date Deposited: | 12 Mar 2015 13:49 |
Last Modified: | 07 Dec 2022 14:58 |
Published Version: | http://dx.doi.org/10.1186/s12968-014-0086-9 |
Status: | Published |
Publisher: | Biomed Central |
Refereed: | Yes |
Identification Number: | 10.1186/s12968-014-0086-9 |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:81410 |
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