Segev, R., Benveniste, M., Hulata, E., Cohen, N., Palevski, A., Kapon, E., Shapira, Y. and Ben-Jacob, E. (2002) Long term behavior of lithographically prepared in vitro neuronal networks. Physical Review Letters, 88 (11). Art. No. 118102. ISSN 1079-7114
We measured the long term spontaneous electrical activity of neuronal networks with different sizes, grown on lithographically prepared substrates and recorded with multi-electrode-array technology. The time sequences of synchronized bursting events were used to characterize network dynamics. All networks exhibit scale-invariant Lévy distributions and long-range correlations. These observations suggest that different-size networks self-organize to adjust their activities over many time scales. As predictions of current models differ from our observations, this calls for revised models.
|Institution:||The University of Leeds|
|Academic Units:||The University of Leeds > Faculty of Engineering (Leeds) > School of Computing (Leeds)|
|Depositing User:||Miss Jamie Grant|
|Date Deposited:||12 Mar 2009 18:44|
|Last Modified:||15 Sep 2014 01:38|
|Publisher:||American Physical Society|