White Rose University Consortium logo
University of Leeds logo University of Sheffield logo York University logo

Long term behavior of lithographically prepared in vitro neuronal networks

Segev, R., Benveniste, M., Hulata, E., Cohen, N., Palevski, A., Kapon, E., Shapira, Y. and Ben-Jacob, E. (2002) Long term behavior of lithographically prepared in vitro neuronal networks. Physical Review Letters, 88 (11). Art. No. 118102. ISSN 1079-7114

Full text available as:

Abstract

We measured the long term spontaneous electrical activity of neuronal networks with different sizes, grown on lithographically prepared substrates and recorded with multi-electrode-array technology. The time sequences of synchronized bursting events were used to characterize network dynamics. All networks exhibit scale-invariant Lévy distributions and long-range correlations. These observations suggest that different-size networks self-organize to adjust their activities over many time scales. As predictions of current models differ from our observations, this calls for revised models.

Item Type: Article
Institution: The University of Leeds
Academic Units: The University of Leeds > Faculty of Engineering (Leeds) > School of Computing (Leeds)
Depositing User: Miss Jamie Grant
Date Deposited: 12 Mar 2009 18:44
Last Modified: 15 Sep 2014 01:38
Published Version: http://dx.doi.org/10.1103/PhysRevLett.88.118102
Status: Published
Publisher: American Physical Society
Identification Number: 10.1103/PhysRevLett.88.118102
URI: http://eprints.whiterose.ac.uk/id/eprint/7964

Actions (repository staff only: login required)