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The infectiousness of tuberculosis patients coinfected with HIV

Escombe, A.R., Moore, D.A.J., Gilman, R.H., Pan, W., Navincopa, M., Ticona, E., Martinez, C., Caviedes, L., Sheen, P., Gonzalez, A., Noakes, C.J., Friedland, J.S. and Evans, C.A. (2008) The infectiousness of tuberculosis patients coinfected with HIV. Plos Medicine, 5 (9). pp. 1387-1397. ISSN 1549-1277


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The current understanding of airborne tuberculosis (TB) transmission is based on classic 1950s studies in which guinea pigs were exposed to air from a tuberculosis ward. Recently we recreated this model in Lima, Peru, and in this paper we report the use of molecular fingerprinting to investigate patient infectiousness in the current era of HIV infection and multidrug-resistant (MDR) TB.

Item Type: Article
Copyright, Publisher and Additional Information: Copyright: © 2008 Escombe et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Institution: The University of Leeds
Academic Units: The University of Leeds > Faculty of Engineering (Leeds) > School of Civil Engineering (Leeds)
Depositing User: Ms Caroline Wilson
Date Deposited: 11 Feb 2009 18:48
Last Modified: 05 Jun 2014 18:09
Published Version: http://dx.doi.org/10.1371/journal.pmed.0050188
Status: Published
Publisher: Public Library of Science
Refereed: Yes
Identification Number: 10.1371/journal.pmed.0050188
URI: http://eprints.whiterose.ac.uk/id/eprint/7783

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