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Rapid detection of hydroxyl groups on solid-phase

Fake, R.E. and Routledge, A. (2004) Rapid detection of hydroxyl groups on solid-phase. Tetrahedron Letters, 45 (48). pp. 8925-8926. ISSN 0040-4039

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Abstract

A rapid method for the qualitative detection of hydroxyl groups on solid-phase has been developed. The method employs N-methylisatoic anhydride to derivatise resin-bound substrates possessing free hydroxyl functionality. The resultant fluorescent ester can be detected by visualisation under a standard laboratory UV lamp at 365 nm excitation.

Item Type: Article
Institution: The University of York
Academic Units: The University of York > Chemistry (York)
Depositing User: York RAE Import
Date Deposited: 04 Mar 2009 17:01
Last Modified: 04 Mar 2009 17:01
Published Version: http://dx.doi.org/10.1016/j.tetlet.2004.09.161
Status: Published
Publisher: Elsevier Science B.V., Amsterdam.
Identification Number: 10.1016/j.tetlet.2004.09.161
URI: http://eprints.whiterose.ac.uk/id/eprint/7584

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