Firth, A.G., Fairlamb, I.J.S., Darley, K. and Baumann, C.G. (2006) Sonogashira alkynylation of unprotected 8-brominated adenosines and guanosines: Fluorescence properties of compact conjugated acetylenes containing a purine ring. Tetrahedron Letters, 47 (21). pp. 3529-3533. ISSN 0040-4039
Full text not available from this repository.Abstract
A practical Sonogashira alkynylation protocol for the preparation of 8-alkynylated adenosines and guanosines has been developed. Protection of the sugar hydroxyl substituents is not required; protection hinders the purification of these products. A preliminary fluorescent study is reported, which shows that the presence of a substituent on the phenylene ring influences the fluorescent properties considerably, an outcome that could be utilized in biological applications.
| Item Type: | Article |
|---|---|
| Academic Units: | The University of York > Chemistry (York) The University of York > Biology (York) |
| Depositing User: | York RAE Import |
| Date Deposited: | 11 Feb 2009 12:30 |
| Last Modified: | 11 Feb 2009 12:30 |
| Published Version: | http://dx.doi.org/10.1016/j.tetlet.2006.03.100 |
| Status: | Published |
| Publisher: | Elsevier Science B.V., Amsterdam. |
| Identification Number: | 10.1016/j.tetlet.2006.03.100 |
| URI: | http://eprints.whiterose.ac.uk/id/eprint/7565 |
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