Quesada, E., Stockley, M., Ragot, J.P., Prime, M.E., Whitwood, A.C. and Taylor, R.J.K. (2004) A versatile, non-biomimetic route to the preussomerins: syntheses of (+ -)-preussomerins F, K and L. Organic and Biomolecular Chemistry, 2 (17). pp. 2483-2495. ISSN 1477-0520
Full text not available from this repository.Abstract
The first total syntheses of the title fungal metabolites preussomerins F, K and L are described and their structures confirmed thereby. The syntheses were achieved following a versatile, unified, non-biomimetic approach, which is easily extendable to prepare other known and novel members of this family. Key steps include the functionalisation of a 2-arylacetal anion, tandem one-pot Friedel–Crafts cyclisation–deprotection, regioselective substrate-directable hydrogenation and reductive-opening of epoxides.
| Item Type: | Article |
|---|---|
| Academic Units: | The University of York > Chemistry (York) |
| Depositing User: | York RAE Import |
| Date Deposited: | 12 Mar 2009 14:43 |
| Last Modified: | 12 Mar 2009 14:43 |
| Published Version: | http://dx.doi.org/10.1039/b407895k |
| Status: | Published |
| Publisher: | Royal Society Chemistry |
| Identification Number: | 10.1039/b407895k |
| URI: | http://eprints.whiterose.ac.uk/id/eprint/7122 |
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