White Rose University Consortium logo
University of Leeds logo University of Sheffield logo York University logo

Slipped-strand mispairing can function as a phase variation mechanism in Escherichia coli

Torres-Cruz, J. and Van der Woude, M.W. (2003) Slipped-strand mispairing can function as a phase variation mechanism in Escherichia coli. Journal of Bacteriology, 185 (23). pp. 6990-6994. ISSN 0021-9193

Full text not available from this repository.

Abstract

Slipped-strand mispairing (SSM) has not been identified as a mechanism of phase variation in Escherichia coli. Using a reporter gene, we show that sequences that cause phase variation by SSM in Haemophilus influenzae also lead to phase variation when introduced onto the chromosome of E. coli, and the frequencies of switching are in the biologically relevant range. Thus, the absence of SSM-mediated phase variation in E. coli does not appear to be due to a mechanistic constraint.

Item Type: Article
Institution: The University of York
Academic Units: The University of York > Hull York Medical School (York)
Depositing User: York RAE Import
Date Deposited: 23 Apr 2009 11:08
Last Modified: 23 Apr 2009 11:08
Published Version: http://dx.doi.org/10.1128/JB.185.23.6990-6994.2003
Status: Published
Publisher: American Society for Microbiology
Identification Number: 10.1128/JB.185.23.6990-6994.2003
URI: http://eprints.whiterose.ac.uk/id/eprint/6582

Actions (repository staff only: login required)