Dumville, J.C., Manca, A., Kitchener, H.C., Smith, A.R.B., Nelson, L. and Torgerson, D.J. (2006) Cost-effectiveness analysis of open colposuspension versus laparoscopic colposuspension in the treatment of urodynamic stress incontinence. BJOG: an International Journal of Obstetrics and Gynaecology, 113 (9). pp. 1014-1022. ISSN 1470-0328
To compare the cost effectiveness of laparoscopic versus open colposuspension for the treatment of female urinary stress incontinence.
Cost utility analysis alongside a randomised controlled trial.
Six gynaecological surgical centres within the UK.
Women with proven stress urinary incontinence requiring surgery.
Open abdominal retropubic colposuspension or laparoscopic colposuspension carried out by experienced surgeons.
MAIN OUTCOME MEASURES
Cost, measured in pounds sterling and generic health-related quality of life, measured using the EQ-5D. The latter was used to estimate patient-specific quality-adjusted life years (QALYs).
Healthcare resource use over 6-month follow up translated into costs of £1805 for the laparoscopic arm and £1433 for the open arm (differential mean cost £372; 95% credibility interval [CrI]: 274–471). At 6 months, QALYs were slightly higher in the laparoscopic arm relative to the open arm (0.005; 95% CrI: −0.012 to 0.023). Therefore, the cost of each extra QALY in the laparoscopic group (the incremental cost-effectiveness ratio [ICER]) was £74,400 at 6 months. At 24 months, the laparoscopic arm again had a higher mean QALY score compared to the open surgery group. Thus, assuming that beyond 6 months the laparoscopic colposuspension would not lead to any significant additional costs compared with open colposuspension, the ICER was reduced to £9300 at 24 months. Extensive sensitivity analyses were carried out to test assumptions made in the base case scenario.
Laparoscopic colposuspension is not cost effective when compared with open colposuspension during the first 6 months following surgery, but it may be cost effective over 24 months.
|Institution:||The University of York|
|Academic Units:||The University of York > Centre for Health Economics (York)
The University of York > Health Sciences (York)
|Depositing User:||York RAE Import|
|Date Deposited:||14 Aug 2009 13:07|
|Last Modified:||14 Aug 2009 13:07|