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Minimizing hypoglycemia while maintaining glycemic control in diabetes

Heller, S. (2008) Minimizing hypoglycemia while maintaining glycemic control in diabetes. Diabetes, 57 (12). pp. 3177-3183. ISSN 0012-1797

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In the accompanying Perspective, Cryer identifies a number of different areas where therapeutic interventions have the potential to reduce hypoglycemia without compromising glycemic control. Some approaches provide well defined clinical benefits, a few offer dramatic reductions in hypoglycemia but remain out of reach for most people while others, although promising have yet to be properly evaluated. (Table 1) In this Perspective, I examine the evidence which underpins these interventions. It is beyond the scope of this article to review the data for each potential intervention in detail but the reader is directed to the appropriate source where appropriate. The Perspective focuses on treatment of Type 1 diabetes as most of the potential specific therapies have been evaluated in this group although I have commented in relation to recent trials of intensive therapy in Type 2 diabetes.

Item Type: Article
Copyright, Publisher and Additional Information: © 2008 American Diabetes Association. This is an author produced version of a paper published in Diabetes. Uploaded in accordance with the publisher's self archiving policy.
Institution: The University of Sheffield
Academic Units: The University of Sheffield > Faculty of Medicine, Dentistry and Health (Sheffield) > School of Medicine (Sheffield)
Depositing User: Sherpa Assistant
Date Deposited: 05 Feb 2009 10:51
Last Modified: 08 Feb 2013 16:57
Published Version: http://dx.doi.org/10.2337/db08-1195
Status: Published
Publisher: American Diabetes Association
Refereed: Yes
Identification Number: 10.2337/db08-1195
URI: http://eprints.whiterose.ac.uk/id/eprint/5594

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