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2-Dimethylarsinothioyl acetic acid identified in a biological sample: the first occurrence of a mammalian arsinothioyl metabolite

Hansen, H.R., Pickford, R., Thomas-Oates, J., Jaspars, M. and Feldmann, J. (2004) 2-Dimethylarsinothioyl acetic acid identified in a biological sample: the first occurrence of a mammalian arsinothioyl metabolite. Angewandte Chemie-International Edition, 43 (3). pp. 337-340. ISSN 1433-7851

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Abstract

Arsenic in sheep's clothing: the first characterization of a thio-organoarsenate compound (2-dimethylarsinothioyl acetic acid) isolated from a biological source (a rare breed of seaweed-eating sheep; see picture) is reported. The result indicates that mammalian arsenic metabolism is much more complex than has been claimed before, which opens up new questions about the toxicity of such organoarsenothio(y)l compounds.

Item Type: Article
Institution: The University of York
Academic Units: The University of York > Chemistry (York)
Depositing User: York RAE Import
Date Deposited: 13 Aug 2009 13:15
Last Modified: 13 Aug 2009 13:15
Published Version: http://dx.doi.org/10.1002/anie.200352740
Status: Published
Publisher: John Wiley & Sons
Identification Number: 10.1002/anie.200352740
URI: http://eprints.whiterose.ac.uk/id/eprint/5559

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