Cowtan, K.D. (2001) Fast Fourier feature recognition. Acta Crystallographica Section D-Biological Crystallography, 57 (10). pp. 1435-1444. ISSN 0907-4449
Various approaches have been demonstrated for the automatic interpretation of crystallographic data in terms of atomic models. The use of a masked Fourier-based search function has some benefits for this task. The application and optimization of this procedure is discussed in detail. The search function also acquires a statistical significance when used with an appropriate electron-density target and weighting, giving rise to improved results at low resolutions. Methods are discussed for building a library of protein fragments suitable for use with this procedure. These methods are demonstrated with the construction of a statistical target for the identification of short helical fragments in the electron density.
|Institution:||The University of York|
|Academic Units:||The University of York > Chemistry (York)|
|Depositing User:||York RAE Import|
|Date Deposited:||13 Aug 2009 15:29|
|Last Modified:||13 Aug 2009 15:29|
|Publisher:||International Union of Crystallography|