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Jolly SAD

Dauter, Z., Dauter, M. and Dodson, E.J. (2002) Jolly SAD. Acta Crystallographica Section D-Biological Crystallography, 58 (3). pp. 494-506. ISSN 0907-4449

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Examples of phasing macromolecular crystal structures based on single-wavelength anomalous dispersion (SAD) show that this approach is more powerful and may have more general application in structural biology than was anticipated. Better data-collection facilities and cryogenic techniques, coupled with powerful programs for data processing, phasing, density modification and automatic model building, means that the SAD approach may gain wide popularity owing to its simplicity, less stringent wavelength requirements and faster data collection and phasing than the multi-wavelength (MAD) approach. It can be performed at any wavelength where anomalous scattering can be observed, in many cases using laboratory X-ray sources.

Item Type: Article
Institution: The University of York
Academic Units: The University of York > Chemistry (York)
Depositing User: York RAE Import
Date Deposited: 13 Aug 2009 11:52
Last Modified: 13 Aug 2009 11:52
Published Version: http://dx.doi.org/10.1107/S090744490200118X
Status: Published
Publisher: International Union of Crystallography
Identification Number: 10.1107/S090744490200118X
URI: http://eprints.whiterose.ac.uk/id/eprint/5520

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