Marriott, H. M., Jackson, L. E., Wilkinson, T. S., Simpson, A. J., Mitchell, T. J., Buttle, D. J., Cross, S. S., Ince, P. G., Hellewell, P. G., Whyte, M. K. B. and Dockrell, D. H. (2008) Reactive oxygen species regulate neutrophil recruitment and survival in pneumococcal pneumonia. American journal of respiratory and critical care medicine, 177 (8). pp. 887-895. ISSN 1535-4970
Full text not available from this repository.Abstract
During pneumococcal pneumonia, NADPH oxidase-derived reactive oxygen species are redundant for host defense but limit neutrophil recruitment and survival. Decreased NADPH oxidase-dependent reactive oxygen species production is well tolerated and improves disease outcome during pneumococcal pneumonia by removing neutrophils from the tight constraints of reactive oxygen species-mediated regulation.
| Item Type: | Article |
|---|---|
| Academic Units: | The University of Sheffield > Faculty of Medicine, Dentistry and Health (Sheffield) > School of Medicine (Sheffield) > Department of Infection & Immunity |
| Depositing User: | Miss Anthea Tucker |
| Date Deposited: | 29 Mar 2012 09:52 |
| Last Modified: | 29 Mar 2012 09:52 |
| Published Version: | http://dx.doi.org/10.1164/rccm.200707-990OC |
| Status: | Published |
| Publisher: | American Thoracic Society |
| Identification Number: | 10.1164/rccm.200707-990OC |
| Related URLs: | |
| URI: | http://eprints.whiterose.ac.uk/id/eprint/43801 |
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