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Interventions for the treatment of oral cavity and oropharyngeal cancer: chemotherapy.

Furness, S, Glenny, AM, Worthington, HV, Pavitt, S, Oliver, R, Clarkson, JE, Macluskey, M, Chan, KK, Conway, DI and CSROC Expert Panel, (2010) Interventions for the treatment of oral cavity and oropharyngeal cancer: chemotherapy. Cochrane Database System Review (9). ISSN 1469-493X


Oral cavity and oropharyngeal cancers are frequently described as part of a group of oral cancers or head and neck cancer. Treatment of oral cavity cancer is generally surgery followed by radiotherapy, whereas oropharyngeal cancers, which are more likely to be advanced at the time of diagnosis, are managed with radiotherapy or chemoradiation. Surgery for oral cancers can be disfiguring and both surgery and radiotherapy have significant functional side effects, notably impaired ability to eat, drink and talk. The development of new chemotherapy agents, new combinations of agents and changes in the relative timing of surgery, radiotherapy, and chemotherapy treatments may potentially bring about increases in both survival and quality of life for this group of patients.

Item Type: Article
Keywords: Antineoplastic Combined Chemotherapy Protocols, Carcinoma, Squamous Cell, Combined Modality Therapy, Humans, Mouth Neoplasms, Oropharyngeal Neoplasms, Randomized Controlled Trials as Topic, Remission Induction, Survival Analysis
Institution: The University of Leeds
Academic Units: The University of Leeds > Faculty of Medicine and Health (Leeds) > School of Medicine (Leeds) > Leeds Institute of Health Sciences (Leeds) > Academic Unit of Psychiatry and Behavioural Sciences (Leeds)
Depositing User: Symplectic Publications
Date Deposited: 06 Jun 2011 15:06
Last Modified: 08 Jul 2014 04:26
Published Version: http://dx.doi.org/10.1002/14651858.CD006386.pub2
Publisher: John Wiley & Sons Inc.
Identification Number: 10.1002/14651858.CD006386.pub2
URI: http://eprints.whiterose.ac.uk/id/eprint/43032

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