Mavranezouli, I., Brazier, J.E., Young, T.A. et al. (1 more author) (2011) Using Rasch analysis to form plausible health states amenable to valuation: the development of CORE-6D from CORE-OM in order to elicit preferences for common mental health problems. Quality of Life Research, 20 (3). pp. 321-333. ISSN 1573-2649
Purpose: To describe a new approach for deriving a preference-based index from a condition specific measure that uses Rasch analysis to develop health states.
Methods: CORE-OM is a 34-item instrument monitoring clinical outcomes of people with common mental health problems. CORE-OM is characterised by high correlation across its domains. Rasch analysis was used to reduce the number of items and response levels in order to produce a set of unidimensionally-behaving items, and to generate a credible set of health states corresponding to different levels of symptom severity using the Rasch item threshold map.
Results: The proposed methodology resulted in the development of CORE-6D, a 2-dimensional health state description system consisting of a unidimensionally-behaving 5-item emotional component and a physical symptom item. Inspection of the Rasch item threshold map of the emotional component helped identify a set of 11 plausible health states, which, combined with the physical symptom item levels, will be used for the valuation of the instrument, resulting in the development of a preference-based index.
Conclusions: This is a useful new approach to develop preference-based measures where the domains of a measure are characterised by high correlation. The CORE-6D preference-based index will enable calculation of Quality Adjusted Life Years in people with common mental health problems.
|Copyright, Publisher and Additional Information:||The attached file is an earlier version of a paper subsequently published in Quality of Life Research in accordance with the publisher's self-archiving policy.|
|Keywords:||Rasch analysis, health-related quality of life, condition-specific measure, preference-based-health, health states, CORE-6D, CORE-OM, mental health, quality-adjusted life years|
|Institution:||The University of Sheffield|
|Academic Units:||The University of Sheffield > University of Sheffield Research Centres and Institutes > Centre for Psychological Services Research (Sheffield)
The University of Sheffield > Faculty of Medicine, Dentistry and Health (Sheffield) > School of Health and Related Research (Sheffield) > Health Economics and Decision Science
The University of Sheffield > Faculty of Medicine, Dentistry and Health (Sheffield) > School of Health and Related Research (Sheffield) > Health Economics and Decision Science > HEDS Discussion Paper Series
|Depositing User:||ScHARR / HEDS (Sheffield)|
|Date Deposited:||05 Apr 2011 14:15|
|Last Modified:||09 Jun 2014 03:40|