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Combining pot, atom and step economy (PASE) in organic synthesis. Synthesis of tetrahydropyran-4-ones

Clarke, Paul A. (orcid.org/0000-0003-3952-359X), Santos, Soraia and Martin, William H. C. (2007) Combining pot, atom and step economy (PASE) in organic synthesis. Synthesis of tetrahydropyran-4-ones. Green Chemistry. pp. 438-440. ISSN 1463-9270

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Abstract

The combination of pot, atom and step economy (PASE) in the synthesis of organic molecules of medium complexity can lead to a significant 'greening' of a synthetic route. This is demonstrated by the synthesis of highly substituted tetrahydropyran-4-ones and is quantified by a series of recognised metrics, which demonstrate the efficiency of combining PASE over conventional synthetic strategies.

Item Type: Article
Keywords: CATALYSIS,LEADS
Institution: The University of York
Academic Units: The University of York > Chemistry (York)
Depositing User: Ms Diana Hilmer
Date Deposited: 12 Oct 2007 17:23
Last Modified: 24 Jul 2016 00:04
Published Version: http://dx.doi.org/10.1039/b700923b
Status: Published
Refereed: Yes
URI: http://eprints.whiterose.ac.uk/id/eprint/3376

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