Kariuki, T.M., Farah, I.O., Yole, D.S., Mwenda, J.M., Van Dam, G.J., Deelder, A.M., Coulson, P.S. and Wilson, R.A. (2004) Parameters of the attenuated schistosome vaccine evaluated in the olive baboon. Infection and Immunity. pp. 5526-5529. ISSN 1098-5522Full text available as:
Five exposures of baboons to the attenuated schistosome vaccine gave greater protection than three exposures, but this attenuation was not sustained when challenge was delayed. Within the scope of the data collected, fecal egg counts and circulating antigen levels did not accurately predict the observed worm burdens. Levels of immunoglobulin G at challenge correlated best with protection, but there was little evidence of a recall response.
|Copyright, Publisher and Additional Information:||Copyright © 2004, American Society for Microbiology|
|Keywords:||IRRADIATED CERCARIA VACCINE, CIRCULATING ANODIC ANTIGEN, PAPIO-ANUBIS, MONOCLONAL-ANTIBODIES, PROTECTIVE IMMUNITY, MANSONI, RESPONSES|
|Academic Units:||The University of York > Biology (York)|
|Depositing User:||Sherpa Assistant|
|Date Deposited:||04 Mar 2005|
|Last Modified:||17 Oct 2013 14:25|