Grigg, R., McCaffrey, S., Sridharan, V., Fishwick, C.W.G., Kilner, C., Korn, S., Bailey, K. and Blacker, J. (2006) Enantioselective synthesis of non-proteinogenic 2-arylallyl-α-amino acids via Pd/In catalytic cascades. Tetrahedron, 62 (52). pp. 12159-12171. ISSN 0040-4020
An efficient synthesis of both R- and S-enantiomers of 2-arylallyl-α-amino acids via a diastereoselective Pd/In mediated catalytic allylation of chiral N-sulfinyl-α-imino esters is described. The potential for further enhancement of molecular complexity and creating contiguous chiral centres by interfacing these processes with catalytic cyclisation–anion capture methodology is demonstrated.
|Copyright, Publisher and Additional Information:||Copyright © 2006 Elsevier Ltd. This is an author produced version of a paper published in Tetrahedron.|
|Institution:||The University of Leeds|
|Academic Units:||The University of Leeds > Faculty of Maths and Physical Sciences (Leeds) > School of Chemistry (Leeds)|
|Depositing User:||Repository Officer|
|Date Deposited:||05 Feb 2007|
|Last Modified:||16 Sep 2016 13:16|