AAV9‐mediated AIRE gene delivery clears circulating antibodies and tissue T‐cell infiltration in a mouse model of autoimmune polyglandular syndrome type‐1

Almaghrabi, S., Azzouz, M. and Tazi Ahnini, R. (2020) AAV9‐mediated AIRE gene delivery clears circulating antibodies and tissue T‐cell infiltration in a mouse model of autoimmune polyglandular syndrome type‐1. Clinical & Translational Immunology, 9. e1166. ISSN 2050-0068

Abstract

Metadata

Authors/Creators:
  • Almaghrabi, S.
  • Azzouz, M.
  • Tazi Ahnini, R.
Copyright, Publisher and Additional Information: © 2020 The Authors. Clinical & Translational Immunology published by John Wiley & Sons Australia, Ltd on behalf of Australian and New Zealand Society for Immunology, Inc. This is an open access article under the terms of the Creative Commons Attribution License, (http://creativecommons.org/licenses/by/4.0/) which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
Keywords: autoimmune polyglandular syndrome type‐1; adeno‐associated virus serotype 9; autoimmune regulator gene; intrathymic injection; gene therapy
Dates:
  • Accepted: 30 July 2020
  • Published (online): 3 September 2020
  • Published: 3 September 2020
Institution: The University of Sheffield
Academic Units: The University of Sheffield > Sheffield Teaching Hospitals
Depositing User: Symplectic Sheffield
Date Deposited: 17 Sep 2020 10:49
Last Modified: 17 Sep 2020 10:49
Status: Published
Publisher: Wiley
Refereed: Yes
Identification Number: https://doi.org/10.1002/cti2.1166

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