The failure of microglia to digest developmental apoptotic cells contributes to the pathology of RNASET2-deficient leukoencephalopathy

Hamilton, N. orcid.org/0000-0002-3299-9133, Rutherford, H.A., Petts, J.J. et al. (6 more authors) (2020) The failure of microglia to digest developmental apoptotic cells contributes to the pathology of RNASET2-deficient leukoencephalopathy. Glia. ISSN 0894-1491

Abstract

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Authors/Creators:
Copyright, Publisher and Additional Information: © 2020 The Authors. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited (http://creativecommons.org/licenses/by/4.0/).
Keywords: developmental apoptosis; leukodystrophy; lysosomal storage disorder; microglia; microglia depletion; RNaseT2; zebrafish
Dates:
  • Accepted: 13 March 2020
  • Published (online): 25 March 2020
Institution: The University of Sheffield
Academic Units: The University of Sheffield > Faculty of Medicine, Dentistry and Health (Sheffield) > Department of Infection and Immunity (Sheffield)
Funding Information:
FunderGrant number
Biotechnology and Biological Sciences Research CouncilBB/M012522/1
Depositing User: Symplectic Sheffield
Date Deposited: 23 Apr 2020 09:07
Last Modified: 23 Apr 2020 09:07
Status: Published online
Publisher: Wiley
Refereed: Yes
Identification Number: https://doi.org/10.1002/glia.23829
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