Chromosome-free bacterial cells are safe and programmable platforms for synthetic biology

Fan, C., Davison, P.A., Habgood, R. et al. (12 more authors) (2020) Chromosome-free bacterial cells are safe and programmable platforms for synthetic biology. Proceedings of the National Academy of Sciences, 117 (12). pp. 6752-6761. ISSN 0027-8424

Abstract

Metadata

Authors/Creators:
  • Fan, C.
  • Davison, P.A.
  • Habgood, R.
  • Zeng, H.
  • Decker, C.M.
  • Gesell Salazar, M.
  • Lueangwattanapong, K.
  • Townley, H.E.
  • Yang, A.
  • Thompson, I.P.
  • Ye, H.
  • Cui, Z.
  • Schmidt, F.
  • Hunter, C.N. https://orcid.org/0000-0003-2533-9783
  • Huang, W.E.
Copyright, Publisher and Additional Information: © 2020 the Author(s). Published by PNAS. This open access article is distributed under Creative Commons Attribution License 4.0 (http://creativecommons.org/licenses/by/4.0/).
Keywords: synthetic biology |; SimCells; minimal genome; bacterial therapy; cancer
Dates:
  • Accepted: 3 February 2020
  • Published (online): 6 March 2020
  • Published: 24 March 2020
Institution: The University of Sheffield
Academic Units: The University of Sheffield > Faculty of Science (Sheffield) > School of Biological Sciences (Sheffield) > Department of Molecular Biology and Biotechnology (Sheffield)
Funding Information:
FunderGrant number
Engineering and Physical Sciences Research CouncilEP/N009746/1
Depositing User: Symplectic Sheffield
Date Deposited: 21 Apr 2020 12:50
Last Modified: 21 Apr 2020 12:50
Status: Published
Publisher: National Academy of Sciences
Refereed: Yes
Identification Number: https://doi.org/10.1073/pnas.1918859117
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