EML4-ALK V3 oncogenic fusion proteins promote microtubule stabilization and accelerated migration through NEK9 and NEK7

O'Regan, L., Barone, G., Adib, R. et al. (10 more authors) (2020) EML4-ALK V3 oncogenic fusion proteins promote microtubule stabilization and accelerated migration through NEK9 and NEK7. Journal of Cell Science. jcs.241505. ISSN 0021-9533

Abstract

Metadata

Authors/Creators:
  • O'Regan, L.
  • Barone, G.
  • Adib, R.
  • Woo, C.G.
  • Jeong, H.J.
  • Richardson, E.L.
  • Richards, M.W..
  • Muller, P.A.J.
  • Collis, S.J. https://orcid.org/0000-0002-7874-1891
  • Fennell, D.A.
  • Choi, J.
  • Bayliss, R.
  • Fry, A.M.
Copyright, Publisher and Additional Information: © 2020. Published by The Company of Biologists Ltd. This is an author-produced version of a paper subsequently published in Journal of Cell Science. Uploaded in accordance with the publisher's self-archiving policy.
Keywords: EML4-ALK; EML4; NEK9; NEK7; NSCLC; Microtubules; Cell migration; Metastasis
Dates:
  • Accepted: 9 March 2020
  • Published (online): 17 March 2020
Institution: The University of Sheffield
Academic Units: The University of Sheffield > Faculty of Medicine, Dentistry and Health (Sheffield) > Department of Human Metabolism (Sheffield)
The University of Sheffield > Faculty of Medicine, Dentistry and Health (Sheffield) > Department of Oncology (Sheffield)
Funding Information:
FunderGrant number
CANCER RESEARCH UKC36435/A12102
Depositing User: Symplectic Sheffield
Date Deposited: 27 Mar 2020 12:18
Last Modified: 27 Mar 2020 12:18
Status: Published online
Publisher: The Company of Biologists
Refereed: Yes
Identification Number: https://doi.org/10.1242/jcs.241505
Related URLs:

Download

Accepted Version


Embargoed until: 17 March 2021

Filename: jcs.241505.full.pdf

Request a copy

Share / Export

Statistics