Accelerated oral nanomedicine discovery from miniaturized screening to clinical production exemplified by paediatric HIV nanotherapies

Giardiello, M. orcid.org/0000-0003-0560-4711, Liptrott, N.J., McDonald, T.O. et al. (7 more authors) (2016) Accelerated oral nanomedicine discovery from miniaturized screening to clinical production exemplified by paediatric HIV nanotherapies. Nature Communications, 7. 13184. ISSN 2041-1723

Abstract

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Copyright, Publisher and Additional Information: © The Author(s) 2016. This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/
Keywords: Administration, Oral; Animals; Anti-HIV Agents; Caco-2 Cells; Cell Membrane Permeability; Child; Drug Delivery Systems; HIV Infections; High-Throughput Screening Assays; Humans; Lopinavir; Male; Nanomedicine; Nanoparticles; Rats; Rats, Sprague-Dawley; Ritonavir; Small Molecule Libraries; Translational Medical Research
Dates:
  • Accepted: 8 September 2016
  • Published (online): 21 October 2016
  • Published: 21 October 2016
Institution: The University of Sheffield
Academic Units: The University of Sheffield > Faculty of Engineering (Sheffield) > Department of Materials Science and Engineering (Sheffield)
Depositing User: Symplectic Sheffield
Date Deposited: 11 Feb 2020 15:37
Last Modified: 11 Feb 2020 15:44
Status: Published
Publisher: Nature Research
Refereed: Yes
Identification Number: https://doi.org/10.1038/ncomms13184
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