Mechanically activated Piezo1 channels of cardiac fibroblasts stimulate p38 mitogen-activated protein kinase activity and interleukin-6 secretion

Blythe, NM, Muraki, K, Ludlow, MJ et al. (12 more authors) (2019) Mechanically activated Piezo1 channels of cardiac fibroblasts stimulate p38 mitogen-activated protein kinase activity and interleukin-6 secretion. Journal of Biological Chemistry, 294 (46). pp. 17395-17408. ISSN 0021-9258

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Authors/Creators:
Copyright, Publisher and Additional Information: © 2019 Blythe et al. This is an open access article under the terms of the Creative Commons Attribution License (CC-BY 4.0), which permits unrestricted use, distribution and reproduction in any medium, provided the original work is properly cited. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
Keywords: ion channel; calcium; p38 MAPK; mitogen-activated protein kinase (MAPK); IL-6; fibroblast; heart; mechanotransduction; patch clamp; signal transduction; cardiac fibroblast
Dates:
  • Published: 15 November 2019
  • Accepted: 4 October 2019
  • Published (online): 4 October 2019
Institution: The University of Leeds
Academic Units: The University of Leeds > Faculty of Maths and Physical Sciences (Leeds) > School of Chemistry (Leeds) > Organic Chemistry (Leeds)
The University of Leeds > Faculty of Medicine and Health (Leeds) > School of Medicine (Leeds) > Leeds Institute of Cardiovascular and Metabolic Medicine (LICAMM) > Discovery & Translational Science Dept (Leeds)
The University of Leeds > Faculty of Medicine and Health (Leeds) > School of Medicine (Leeds) > Leeds Institute of Cardiovascular and Metabolic Medicine (LICAMM) > Specialist Science Education Dept (Leeds)
Funding Information:
FunderGrant number
British Heart FoundationFS/15/48/31665
Depositing User: Symplectic Publications
Date Deposited: 14 Oct 2019 12:25
Last Modified: 09 Dec 2019 16:11
Status: Published
Publisher: American Society for Biochemistry and Molecular Biology
Identification Number: https://doi.org/10.1074/jbc.ra119.009167
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