Improved Understanding of Cefixime Trihydrate Reactive Crystallization and Process Scale-up with the Aid of PAT

Yu, S, Zhang, Y and Wang, XZ (2019) Improved Understanding of Cefixime Trihydrate Reactive Crystallization and Process Scale-up with the Aid of PAT. Organic Process Research and Development, 23 (2). pp. 177-188. ISSN 1083-6160

Abstract

Metadata

Authors/Creators:
  • Yu, S
  • Zhang, Y
  • Wang, XZ
Copyright, Publisher and Additional Information: © 2019, American Chemical Society. This document is the Accepted Manuscript version of a Published Work that appeared in final form in Organic Process Research and Development © American Chemical Society after peer review and technical editing by the publisher. To access the final edited and published work see https://doi.org/10.1021/acs.oprd.8b00190.
Keywords: reactive crystallization; cefixime trihydrate; process analytical technology; particle size distribution; crystallinity
Dates:
  • Published: 15 February 2019
  • Accepted: 18 December 2018
  • Published (online): 10 January 2019
Institution: The University of Leeds
Academic Units: The University of Leeds > Faculty of Engineering (Leeds) > School of Chemical & Process Engineering (Leeds)
Depositing User: Symplectic Publications
Date Deposited: 12 Aug 2019 09:42
Last Modified: 12 Aug 2019 09:42
Status: Published
Publisher: American Chemical Society
Identification Number: https://doi.org/10.1021/acs.oprd.8b00190
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Embargoed until: 10 January 2020

Filename: R2%20PAT%20Aided%20Identification%20Operational%20Spaces.pdf

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