Mucoadhesive electrospun patch delivery of lidocaine to the oral mucosa and investigation of spatial distribution in tissue using MALDI-mass spectrometry imaging

Clitherow, K.H., Murdoch, C. orcid.org/0000-0001-9724-122X, Spain, S.G. orcid.org/0000-0001-7241-5713 et al. (7 more authors) (2019) Mucoadhesive electrospun patch delivery of lidocaine to the oral mucosa and investigation of spatial distribution in tissue using MALDI-mass spectrometry imaging. Molecular Pharmaceutics, 16 (9). pp. 3948-3956. ISSN 1543-8384

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Item Type: Article
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© 2019 American Chemical Society. This is an open access article published under a Creative Commons Attribution (http://creativecommons.org/licenses/by/4.0) License, which permits unrestricted use, distribution and reproduction in any medium, provided the author and source are cited.

Keywords: Electrospinning; lidocaine; oral mucosa; ex vivo tissue permeation; MALDI-mass spectrometry imaging; drug distribution in tissue
Dates:
  • Accepted: 30 July 2019
  • Published (online): 30 July 2019
  • Published: 3 September 2019
Institution: The University of Sheffield
Academic Units: The University of Sheffield > Faculty of Medicine, Dentistry and Health (Sheffield) > School of Clinical Dentistry (Sheffield)
The University of Sheffield > Faculty of Science (Sheffield) > Department of Chemistry (Sheffield)
Depositing User: Symplectic Sheffield
Date Deposited: 07 Aug 2019 08:53
Last Modified: 25 Nov 2020 11:26
Status: Published
Publisher: American Chemical Society (ACS)
Refereed: Yes
Identification Number: 10.1021/acs.molpharmaceut.9b00535
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