Integrin α11β1 regulates cancer stromal stiffness and promotes tumorigenicity and metastasis in non-small cell lung cancer

Navab, R., Strumpf, D., To, C. et al. (22 more authors) (2016) Integrin α11β1 regulates cancer stromal stiffness and promotes tumorigenicity and metastasis in non-small cell lung cancer. Oncogene, 35 (15). pp. 1899-1908. ISSN 0950-9232

Abstract

Metadata

Authors/Creators:
  • Navab, R.
  • Strumpf, D.
  • To, C.
  • Pasko, E.
  • Kim, K.S.
  • Park, C.J.
  • Hai, J.
  • Liu, J.
  • Jonkman, J.
  • Barczyk, M.
  • Bandarchi, B.
  • Wang, Y.H.
  • Venkat, K.
  • Ibrahimov, E.
  • Pham, N.-A.
  • Ng, C.
  • Radulovich, N.
  • Zhu, C.-Q.
  • Pintilie, M.
  • Wang, D. https://orcid.org/0000-0003-0068-1005
  • Lu, A.
  • Jurisica, I.
  • Walker, G.C.
  • Gullberg, D.
  • Tsao, M.-S.
Copyright, Publisher and Additional Information: © 2016 Macmillan Publishers Limited. This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/4.0/
Keywords: Adenocarcinoma; Animals; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Collagen; Crosses, Genetic; Elasticity; Extracellular Matrix Proteins; Fibroblasts; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Heterografts; Humans; Integrin alpha Chains; Integrin beta1; Integrins; Lung Neoplasms; Mice; Mice, Inbred Strains; Mice, Knockout; Mice, SCID; Neoplasm Invasiveness; Neoplasm Proteins; Protein Kinases; Receptors, Collagen; Signal Transduction; Stromal Cells
Dates:
  • Accepted: 29 May 2015
  • Published (online): 6 July 2015
  • Published: 14 April 2016
Institution: The University of Sheffield
Academic Units: The University of Sheffield > Faculty of Medicine, Dentistry and Health (Sheffield) > Department of Neuroscience (Sheffield)
Depositing User: Symplectic Sheffield
Date Deposited: 16 May 2019 09:14
Last Modified: 16 May 2019 09:16
Status: Published
Publisher: Springer Nature
Refereed: Yes
Identification Number: https://doi.org/10.1038/onc.2015.254
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