Dual Role of Ribosome-Binding Domain of NAC as a Potent Suppressor of Protein Aggregation and Aging-Related Proteinopathies

Shen, K, Gamerdinger, M, Chan, R et al. (12 more authors) (2019) Dual Role of Ribosome-Binding Domain of NAC as a Potent Suppressor of Protein Aggregation and Aging-Related Proteinopathies. Molecular Cell, 74 (4). 729-741.e7. ISSN 1097-2765

Abstract

Metadata

Authors/Creators:
  • Shen, K
  • Gamerdinger, M
  • Chan, R
  • Gense, K
  • Martin, EM
  • Sachs, N
  • Knight, PD
  • Schlömer, R
  • Calabrese, AN
  • Stewart, KL
  • Leiendecker, L
  • Baghel, A
  • Radford, SE https://orcid.org/0000-0001-9668-6366
  • Frydman, J
  • Deuerling, E
Copyright, Publisher and Additional Information: (c) 2019 The Authors. Published by Elsevier Inc. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
Keywords: proteostasis; chaperone; nascent polypeptide-associated complex; polyglutamine (PolyQ) proteins; Aβ40; protein aggregation; proteotoxicity; organismal fitness; age-related proteinopathies
Dates:
  • Published: 16 May 2019
  • Accepted: 8 March 2019
  • Published (online): 11 April 2019
Institution: The University of Leeds
Academic Units: The University of Leeds > Faculty of Biological Sciences (Leeds) > School of Molecular and Cellular Biology (Leeds) > Biomolecular Mass Spectroscopy (Leeds)
The University of Leeds > Faculty of Biological Sciences (Leeds) > School of Molecular and Cellular Biology (Leeds) > Structural Molecular Biology (Leeds)
Depositing User: Symplectic Publications
Date Deposited: 12 Mar 2019 11:09
Last Modified: 17 May 2019 14:29
Status: Published
Publisher: Elsevier
Identification Number: https://doi.org/10.1016/j.molcel.2019.03.012

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